Second‐trimester maternal serum screening using alpha‐fetoprotein, human chorionic gonadotrophin, and unconjugated oestriol: experience of a regional …

SF Goodburn, JRW Yates, PR Raggatt… - Prenatal …, 1994 - Wiley Online Library
Over a 2‐year period from January 1991 to December 1992, second‐trimester maternal
serum screening for Down's syndrome using alpha‐fetoprotein (aFP), human chorionic …

Antenatal maternal serum screening for Down's syndrome: results of a demonstration project.

NJ Wald, A Kennard, JW Densem, HS Cuckle… - British Medical …, 1992 - bmj.com
OBJECTIVES--To assess the implementation of antenatal screening for Down's syndrome in
practice, using individual risk estimates based on maternal age and the three serum …

Appraisal of a new scheme for prenatal screening for Down's syndrome.

TA Sheldon, J Simpson - British Medical Journal, 1991 - bmj.com
OBJECTIVE--To appraise a new method of prenatal screening for Down's syndrome based
on maternal serum concentrations of alpha fetoprotein, unconjugated oestriol, and human …

Maternal serum screening for Down's syndrome: the effect of routine ultrasound scan determination of gestational age and adjustment for maternal weight

NJ Wald, HS Cuckle, JW Densem… - … Journal of Obstetrics …, 1992 - Wiley Online Library
Objective To investigate the effect of using a routine ultrasound estimate of gestational age
and maternal weight adjustment on maternal serum alpha‐fetoprotein (AFP), unconjugated …

Implementation of an antenatal serum screening programme for Down's syndrome in two districts (Brighton and Eastbourne)

M Piggott, P Wilkinson, J Bennett… - Journal of Medical …, 1994 - journals.sagepub.com
Objectives-To evaluate the introduction to two health districts of an antenatal serum
screening programme for Down's syndrome using the triple test-measurement of a …

Maternal serum screening for Down's syndrome in early pregnancy.

NJ Wald, HS Cuckle, JW Densem, K Nanchahal… - British medical …, 1988 - bmj.com
The possibility of improving the effectiveness of antenatal screening for Down's syndrome by
measuring human chorionic gonadotrophin concentrations in maternal serum during the …

Four‐marker serum screening for Down's syndrome

NJ Wald, JW Densem, D Smith, GG Klee - Prenatal diagnosis, 1994 - Wiley Online Library
The value of measuring the separate sub‐units of human chorionic gonadotrophin (free α‐
hCG and free β‐hCG) instead of total hCG together with alpha‐fetoprotein (AFP) and …

Maternal serum unconjugated oestriol as an antenatal screening test for Down's syndrome

NJ Wald, HS Cuckle, JW Densem… - … Journal of Obstetrics …, 1988 - Wiley Online Library
The median maternal serum unconjugated oestriol level between 13 and 27 weeks
gestation in 77 pregnancies associated with Down's syndrome was lower than the median …

Second‐trimester maternal serum alpha‐fetoprotein and human chorionic gonadotrophin screening for Down's syndrome in Hong Kong

YH Lam, A Ghosh, MHY Tang… - … in Affiliation With the …, 1998 - Wiley Online Library
Second‐trimester maternal serum screening for fetal Down's syndrome is well established in
many Western countries. Its usefulness and acceptability is unknown in the Asian countries …

Screening for fetal Down's syndrome with maternal serum markers—An experience in Italy

G Mancini, M Perona, D Dalľamico, C Bollati… - Prenatal …, 1991 - Wiley Online Library
The effectiveness of maternal serum alpha-fetoprotein, unconjugated oestriol, and human
chorionic gonadotrophin in screening for Down's syndrome (DS) was evaluated on 840 …