Molecular pathogenesis of myocardial remodeling and new potential therapeutic targets in chronic heart failure

G Distefano, P Sciacca - Italian journal of pediatrics, 2012 - Springer
It is well known that the natural history of chronic heart failure (CHF), regardless of age and
aetiology, is characterized by progressive cardiac dysfunction refractory to conventional …

Cardiac hypertrophy: molecular and cellular events

JE Carreño, F Apablaza, MP Ocaranza… - Revista Española de …, 2006 - Elsevier
Cardiac hypertrophy is one of the main ways in which cardiomyocytes respond to
mechanical and neurohormonal stimuli. It enables myocytes to increase their work output …

Cardiac remodeling and failure: from molecules to man (Part I)

PWM Fedak, S Verma, RD Weisel, RK Li - Cardiovascular Pathology, 2005 - Elsevier
The process of heart failure appears to be a common and coordinated response to cardiac
injury and dysfunction. The contemporary mechanistic viewpoint that predictable, shared …

Hipertrofia cardiaca: eventos moleculares y celulares

JE Carreño, F Apablaza, MP Ocaranza… - Revista española de …, 2006 - Elsevier
Cardiac hypertrophy is one of the main ways in which cardiomyocytes respond to
mechanical and neurohormonal stimuli. It enables myocytes to increase their work output …

Mechanisms contributing to cardiac remodelling

QQ Wu, Y Xiao, Y Yuan, ZG Ma, HH Liao, C Liu… - Clinical …, 2017 - portlandpress.com
Cardiac remodelling is classified as physiological (in response to growth, exercise and
pregnancy) or pathological (in response to inflammation, ischaemia, ischaemia/reperfusion …

Subcellular remodeling as a viable target for the treatment of congestive heart failure

NS Dhalla, MR Dent, PS Tappia… - Journal of …, 2006 - journals.sagepub.com
It is now well known that congestive heart failure (CHF) is invariably associated with cardiac
hypertrophy, and changes in the shape and size of cardiomyocytes (cardiac remodeling) are …

Subcellular remodelling may induce cardiac dysfunction in congestive heart failure

NS Dhalla, HK Saini-Chohan… - Cardiovascular …, 2009 - academic.oup.com
It is commonly held that cardiac remodelling, represented by changes in muscle mass, size,
and shape of the heart, explains the progression of congestive heart failure (CHF). However …

[图书][B] Cardiac remodeling: molecular mechanisms

BI Jugdutt, NS Dhalla - 2013 - books.google.com
The main objective of Cardiac Remodeling: Molecular Mechanisms is to summarize the
major research advances in molecular, biochemical and translational aspects of cardiac …

Molecular and cellular mechanisms of myocardial remodeling

M Maytin, W S. Colucci - Journal of nuclear cardiology, 2002 - Springer
Myocardial remodeling is inextricably intertwined with the development and progression of
heart failure. It is characterized by alterations in ventricular geometry and function. At the …

Advances in the molecular mechanisms of heart failure

WR MacLellan - Current opinion in cardiology, 2000 - journals.lww.com
Congestive heart failure is a common clinical problem resulting in significant morbidity and
mortality. Although considerable progress has been made in elucidating the …