Non peptidic urotensin II antagonists: perspectives for a new class of drugs
A Cosenzi - … & Hematological Agents in Medicinal Chemistry …, 2008 - ingentaconnect.com
Urotensin II (U-II) is a cyclic peptide isolated from a fish. Subsequently, human U-II and its
receptor were identified. In rat thoracic aorta U-II triggers powerful vasoconstrictor activity …
receptor were identified. In rat thoracic aorta U-II triggers powerful vasoconstrictor activity …
Effects of urotensin-II on cerebral blood flow and ischemia in anesthetized rats
Urotensin-II (U-II) is a cyclic peptide identified recently in many mammalian species
including man. U-II and its receptor are expressed in the central nervous system, in the …
including man. U-II and its receptor are expressed in the central nervous system, in the …
Role of urotensin II and its receptor in health and disease
J McDonald, M Batuwangala, DG Lambert - Journal of anesthesia, 2007 - Springer
Abstract Urotensin II (U-II) is currently the most potent vasoconstrictor identified. This action
is brought about via activation of a G q/11-protein coupled receptor (UT receptor). U-II …
is brought about via activation of a G q/11-protein coupled receptor (UT receptor). U-II …
Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failure
FD Russell, D Meyers, AJ Galbraith… - American Journal …, 2003 - journals.physiology.org
Human urotensin-II (hU-II) is the most potent endogenous cardiostimulant identified to date.
We therefore determined whether hU-II has a possible pathological role by investigating its …
We therefore determined whether hU-II has a possible pathological role by investigating its …
Plasma urotensin II levels in primary Raynaud's phenomenon and systemic sclerosis
N Gözel, A Karataş, M Yardim… - Turkish Journal of …, 2017 - journals.tubitak.gov.tr
Background/aim: The pathogenesis of Raynaud's phenomenon (RP) has not yet been fully
elucidated. RP is characterized by exaggerated cold-induced vasoconstriction. Urotensin II …
elucidated. RP is characterized by exaggerated cold-induced vasoconstriction. Urotensin II …
Urotensin-II as a promising key-point of cardiovascular disturbances sequel
A Avagimyan, A Kajaia, L Gabunia… - Current Problems in …, 2022 - Elsevier
Arterial hypertension is a highly urgent problem of modern medicine since the crisis of blood
pressure control remains open, due to the increasing number of uncontrolled arterial …
pressure control remains open, due to the increasing number of uncontrolled arterial …
Increased plasma urotensin-II and carotid atherosclerosis are associated with vascular dementia
Y Ban, T Watanabe, T Suguro, T Matsuyama… - … of atherosclerosis and …, 2009 - jstage.jst.go.jp
Aim: Human urotensin-II (UII) is a cyclic neuropeptide with potent vasoconstrictive activity in
the vasculature. The expression of UII and its receptor (UT) mRNA is detected at high levels …
the vasculature. The expression of UII and its receptor (UT) mRNA is detected at high levels …
[HTML][HTML] Urotensin 2 and oxidative stress levels in maternal serum in pregnancies complicated by intrauterine growth restriction
Background and objectives: In this study, the aim was to investigate Urotensin 2 (U-II) levels
and oxidant/antioxidant system parameters in pregnancies with intrauterine growth …
and oxidant/antioxidant system parameters in pregnancies with intrauterine growth …
Association of urotensin Ⅱ with angiographic severity of coronary artery disease
L Zhang, Y Ke, Y Wang, X Li, L Chen - Journal of Geriatric Cardiology, 2007 - jgc301.com
Objective The goal of this study was to examine the association between urotensin Ⅱ (U Ⅱ)
concentration and the severity of coronary artery disease (CAD). Methods We studied U Ⅱ …
concentration and the severity of coronary artery disease (CAD). Methods We studied U Ⅱ …
High plasma concentrations of human urotensin II do not alter local or systemic hemodynamics in man
IB Wilkinson, JT Affolter, SL De Haas… - Cardiovascular …, 2002 - academic.oup.com
Abstract Objective: Human urotensin II (hUII) is an endocrine hormone that acts as a potent
arterial vasoconstrictor in both in vitro and in vivo studies in animals. We examined, for the …
arterial vasoconstrictor in both in vitro and in vivo studies in animals. We examined, for the …