TH17 cytokines in autoimmune neuro-inflammation
B Becher, BM Segal - Current opinion in immunology, 2011 - Elsevier
It has been firmly established that IL-23 polarized TH17 cells are potent effectors in the
pathogenesis of experimental autoimmune encephalitomyelitis (EAE). However, the relative …
pathogenesis of experimental autoimmune encephalitomyelitis (EAE). However, the relative …
The role of TH17 cells in multiple sclerosis: Therapeutic implications
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS) where immunopathology is thought to be mediated by myelin-reactive CD4+ T …
system (CNS) where immunopathology is thought to be mediated by myelin-reactive CD4+ T …
Th17 cells and inflammation in neurological disorders: Possible mechanisms of action
Y Shi, B Wei, L Li, B Wang, M Sun - Frontiers in immunology, 2022 - frontiersin.org
Neurological disorders (NDs) are one of the leading causes of global death. A sustained
neuroinflammatory response has been reported to be associated with the pathogenesis of …
neuroinflammatory response has been reported to be associated with the pathogenesis of …
Current views on the roles of Th1 and Th17 cells in experimental autoimmune encephalomyelitis
Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis
(EAE), are autoimmune demyelinating diseases of the central nervous system (CNS) …
(EAE), are autoimmune demyelinating diseases of the central nervous system (CNS) …
IL-23 modulated myelin-specific T cells induce EAE via an IFNγ driven, IL-17 independent pathway
MA Kroenke, BM Segal - Brain, behavior, and immunity, 2011 - Elsevier
Experimental autoimmune encephalomyelitis (EAE) is an inflammatory demyelinating
disease of the central nervous system (CNS) mediated by myelin-reactive CD4+ T cells. An …
disease of the central nervous system (CNS) mediated by myelin-reactive CD4+ T cells. An …
Th17 cells in autoimmune demyelinating disease
BM Segal - Seminars in immunopathology, 2010 - Springer
Recently published studies in multiple sclerosis (MS) and experimental autoimmune
encephalomyelitis (EAE) have demonstrated an association between the development of …
encephalomyelitis (EAE) have demonstrated an association between the development of …
Th17 cells in central nervous system autoimmunity
C Sie, T Korn, M Mitsdoerffer - Experimental neurology, 2014 - Elsevier
Multiple sclerosis (MS) is the most important autoimmune disease of the central nervous
system (CNS). Its animal model experimental autoimmune encephalomyelitis (EAE) has …
system (CNS). Its animal model experimental autoimmune encephalomyelitis (EAE) has …
Interleukin-17 in chronic inflammatory neurological diseases
J Milovanovic, A Arsenijevic, B Stojanovic… - Frontiers in …, 2020 - frontiersin.org
A critical role for IL-17, a cytokine produced by T helper 17 (Th17) cells, has been indicated
in the pathogenesis of chronic inflammatory and autoimmune diseases. A positive effect of …
in the pathogenesis of chronic inflammatory and autoimmune diseases. A positive effect of …
Th17 cells, γδ T cells and their interplay in EAE and multiple sclerosis
AM McGinley, SC Edwards, M Raverdeau… - Journal of …, 2018 - Elsevier
Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis
(MS) that shares many features with the human disease. This review will focus on the role of …
(MS) that shares many features with the human disease. This review will focus on the role of …
Roles of T helper 17 cells and interleukin‐17 in neuroautoimmune diseases with emphasis on multiple sclerosis and Guillain‐Barré syndrome as well as their animal …
X Wang, C Ma, J Wu, J Zhu - Journal of Neuroscience …, 2013 - Wiley Online Library
The identification of T helper 17 (Th17) cells challenges the Th1/Th2 paradigm of the
immune response and invites intensive exploration of their mechanisms and functions in the …
immune response and invites intensive exploration of their mechanisms and functions in the …