Defining the path forward for biomarkers to address unmet needs in inflammatory bowel diseases

G Honig, C Heller… - Inflammatory bowel …, 2020 - academic.oup.com
Despite major advances in the inflammatory bowel diseases field, biomarkers to enable
personalized and effective management are inadequate. Disease course and treatment …

Challenges in IBD research: precision medicine

LA Denson, M Curran, DPB McGovern… - Inflammatory bowel …, 2019 - academic.oup.com
Precision medicine is part of five focus areas of the Challenges in IBD research document,
which also includes preclinical human IBD mechanisms, environmental triggers, novel …

New biomarkers for diagnosing inflammatory bowel disease and assessing treatment outcomes

EL Barnes, R Burakoff - Inflammatory bowel diseases, 2016 - academic.oup.com
Despite advances in our understanding of the pathophysiology underlying inflammatory
bowel disease, there remains a significant need for biomarkers that can differentiate …

Challenges in IBD Research 2024: Precision Medicine

S Syed, BS Boland, LT Bourke, LA Chen… - Inflammatory Bowel …, 2024 - academic.oup.com
Precision medicine is part of 5 focus areas of the Challenges in IBD Research 2024
research document, which also includes preclinical human IBD mechanisms, environmental …

[HTML][HTML] Biomarker discovery for personalized therapy selection in inflammatory bowel diseases: challenges and promises

D Alsoud, S Vermeire, B Verstockt - Current Research in Pharmacology …, 2022 - Elsevier
The past decades witnessed a significant stride in deciphering the pathophysiology of
inflammatory bowel disease, which further advanced drug development adding several new …

Biomarkers of inflammatory bowel disease: from classical laboratory tools to personalized medicine

E Viennois, Y Zhao, D Merlin - Inflammatory bowel diseases, 2015 - academic.oup.com
Diagnostics of inflammatory bowel diseases (IBDs) currently relies on a combination of
biological and morphological tests. The current method of diagnostic remains a critical …

The current status of molecular biomarkers for inflammatory bowel disease

Z Alghoul, C Yang, D Merlin - Biomedicines, 2022 - mdpi.com
Diagnosis and prognosis of inflammatory bowel disease (IBD)—a chronic inflammation that
affects the gastrointestinal tract of patients—are challenging, as most clinical symptoms are …

An update on diagnostic and prognostic biomarkers in inflammatory bowel disease

AS Day, ST Leach, DA Lemberg - Expert Review of Molecular …, 2017 - Taylor & Francis
Introduction: Diagnosis of the chronic inflammatory bowel diseases relies upon initial
recognition of an inflammatory condition, followed by definitive endoscopic, histological and …

Utility of biomarkers in the management of inflammatory bowel disease

G Kochhar, B Lashner - Current treatment options in gastroenterology, 2017 - Springer
Opinion statement Inflammatory bowel disease (IBD) is comprised of complex clinical and
pathological conditions. It runs a chronic course, and proper management requires constant …

Precision medicine in inflammatory bowel diseases: challenges and considerations for the path forward

A Ricciuto, I Rauter, DPB McGovern, RM Mader… - …, 2022 - gastrojournal.org
A fundamental first challenge is that current IBD diagnostic and classification schemes, such
as the Lennard-Jones criteria and Montreal classification, 3 do not capture the significant …