Vitamin E is the last of all vitamins whose essentiality is not yet understood. Its widely
accepted role as a lipophilic antioxidant has been questioned, since proof of its in vivo …

The discovery of vitamin E will have its 100th anniversary in 2022, but we still have more
questions than answers regarding the biological functions and the essentiality of vitamin E …

During the last 90 years since the discovery of vitamin E, research has focused on different
properties of this molecule, the focus often depending on the specific techniques and …

Since its discovery, vitamin E has been extensively researched by a large number of
investigators in an attempt to fully understand its role in a variety of pathophysiological …

Vitamin E is an essential nutrient that was discovered in the 1920s. Many of the
physiological functions of vitamin E, including its antioxidative effects, have been studied for …

A hundred years have passed since vitamin E was identified as an essential micronutrient
for mammals. Since then, many biological functions of vitamin E have been unraveled in …

Natural vitamin E includes four tocopherols and four tocotrienols. RRR-α-tocopherol is the
most abundant form in nature and has the highest biological activity. Although vitamin E is …

Vitamin E, comprising tocopherols and tocotrienols, is mainly known as an antioxidant. The
aim of this review is to summarize the molecular mechanisms and signaling pathways linked …

Although vitamin E has been recognized as a critical micronutrient to neuronal health for
more than half a century, vitamin E transport and regulation in the brain remain a mystery …

Vitamin A, acting through its metabolite, all-trans-retinoic acid, is a potent transcriptional
regulator affecting expression levels of hundreds of genes through retinoic acid response …