Amyloid-β (29− 42) dimer formations studied by a multicanonical− multioverlap molecular dynamics simulation
Amyloid-β peptides are known to form amyloid fibrils and are considered to play an
important role in Alzheimer's disease. Amyloid-β (29− 42) is a fragment of the amyloid-β …
important role in Alzheimer's disease. Amyloid-β (29− 42) is a fragment of the amyloid-β …
Dimerization process of amyloid-β (29–42) studied by the Hamiltonian replica-permutation molecular dynamics simulations
The amyloid-β peptides form amyloid fibrils which are associated with Alzheimer's disease.
Amyloid-β (29–42) is its C-terminal fragment and a critical determinant of the amyloid …
Amyloid-β (29–42) is its C-terminal fragment and a critical determinant of the amyloid …
Oligomer formation of amyloid-β (29–42) from its monomers using the Hamiltonian replica-permutation molecular dynamics simulation
Oligomers of amyloid-β peptides (Aβ) are formed during the early stage of the
amyloidogenesis process and exhibit neurotoxicity. The oligomer formation process of Aβ …
amyloidogenesis process and exhibit neurotoxicity. The oligomer formation process of Aβ …
Replica-permutation molecular dynamics simulations of an amyloid-β (16–22) peptide and polyphenols
Aggregates of amyloid-β (Aβ) peptides, such as oligomers and amyloid fibrils, are related to
Alzheimer's disease. Polyphenols are known to inhibit the aggregation of Aβ peptides. We …
Alzheimer's disease. Polyphenols are known to inhibit the aggregation of Aβ peptides. We …
Computational Study on the Structural Diversity of Amyloid Beta Peptide (Aβ10-35) Oligomers
S Jang, S Shin - The Journal of Physical Chemistry B, 2008 - ACS Publications
We studied the oligomerization of Alzheimer amyloid beta peptide (Aβ) using a replica
exchange molecular dynamics (REMD) simulation. The simulation was performed with Aβ10 …
exchange molecular dynamics (REMD) simulation. The simulation was performed with Aβ10 …
Construction of the free energy landscape of peptide aggregation from molecular dynamics simulations
L Riccardi, PH Nguyen, G Stock - Journal of Chemical Theory and …, 2012 - ACS Publications
To describe the structure and dynamics of oligomers during peptide aggregation, a method
is proposed that considers both the intramolecular and intermolecular structures of the …
is proposed that considers both the intramolecular and intermolecular structures of the …
Key residue for aggregation of amyloid-β peptides
SG Itoh, M Yagi-Utsumi, K Kato… - ACS Chemical …, 2022 - ACS Publications
It is known that oligomers of amyloid-β (Aβ) peptide are associated with Alzheimer's disease.
Aβ has two isoforms: Aβ40 and Aβ42. Although the difference between Aβ40 and Aβ42 is …
Aβ has two isoforms: Aβ40 and Aβ42. Although the difference between Aβ40 and Aβ42 is …
Molecular Mechanism and Kinetics of Amyloid-β42 Aggregate Formation: A Simulation Study
As an important neuropathological hallmark of Alzheimer's disease (AD), the oligomerization
of amyloid-β (Aβ) peptides has been intensively investigated in both theoretical and …
of amyloid-β (Aβ) peptides has been intensively investigated in both theoretical and …
[HTML][HTML] Probing oligomerization of amyloid beta peptide in silico
L Dorosh, M Stepanova - Molecular BioSystems, 2017 - pubs.rsc.org
Aggregation of amyloid β (Aβ) peptide is implicated in fatal Alzheimer's disease, for which no
cure is available. Understanding the mechanisms responsible for this aggregation is …
cure is available. Understanding the mechanisms responsible for this aggregation is …
Computer Simulation Studies of Aβ37–42 Aggregation Thermodynamics and Kinetics in Water and Salt Solution
YI Yang, YQ Gao - The Journal of Physical Chemistry B, 2015 - ACS Publications
In vivo self-assembly of proteins into aggregates known as amyloids is related to many
diseases. Although a large number of studies have been performed on the formation of …
diseases. Although a large number of studies have been performed on the formation of …
相关搜索
- amyloid β replica permutation
- amyloid β dimer formations
- amyloid β molecular dynamics
- amyloid β dimerization process
- amyloid β42 aggregate formation
- dynamics simulations energy landscape
- amyloid β42 molecular mechanism
- aggregate formation molecular mechanism
- dynamics simulations peptide aggregation
- molecular dynamics replica permutation
- amyloid β oligomer formation