Synthesis and toxicity characterization of carbon coated iron oxide nanoparticles with highly defined size distributions

RG Mendes, B Koch, A Bachmatiuk… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Background Iron oxide nanoparticles hold great promise for future biomedical applications.
To this end numerous studies on iron oxide nanoparticles have been conducted. One aspect …

Assessing iron oxide nanoparticle toxicity in vitro: current status and future prospects

SJH Soenen, M De Cuyper - Nanomedicine, 2010 - Future Medicine
The in vitro labeling of stem or therapeutic cells with engineered nanoparticles with the aim
of transplanting these cells into live animals and, for example, noninvasively monitoring their …

Rod‐shaped iron oxide nanoparticles are more toxic than sphere‐shaped nanoparticles to murine macrophage cells

JH Lee, JE Ju, BI Kim, PJ Pak, EK Choi… - Environmental …, 2014 - Wiley Online Library
Variable sizes of nanoparticles, ranging from nano to micro scale, are of toxicological
interest. In the present study, the authors hypothesized that, in addition to the size, the shape …

In vitro cytotoxicity of iron oxide nanoparticles: effects of chitosan and polyvinyl alcohol as stabilizing agents

PA Tran, HT Nguyen, K Fox, N Tran - Materials Research …, 2018 - iopscience.iop.org
Iron oxide magnetic nanoparticles have significant potential in biomedical applications such
as in diagnosis, imaging and therapeutic agent delivery. The choice of stabilizers and …

Cellular internalization and detailed toxicity analysis of protein‐immobilized iron oxide nanoparticles

P Sanganeria, S Sachar, S Chandra… - … Research Part B …, 2015 - Wiley Online Library
Iron oxide nanoparticles (IONPs) have been extensively used for biomedical applications
like in the diagnosis and treatment of various diseases, as contrast agents in magnetic …

Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications

SM Dadfar, K Roemhild, NI Drude… - Advanced drug delivery …, 2019 - Elsevier
Many different iron oxide nanoparticles have been evaluated over the years, for a wide
variety of biomedical applications. We here summarize the synthesis, surface …

In vitro evaluation of the cytotoxicity of iron oxide nanoparticles with different coatings and different sizes in A3 human T lymphocytes

E Ying, HM Hwang - Science of the total environment, 2010 - Elsevier
The ever expanding use of engineered nanoscaled materials has brought about a
commensurate growth in concern about their potential risks to human and environmental …

Cytotoxic effects of iron oxide nanoparticles and implications for safety in cell labelling

SJH Soenen, U Himmelreich, N Nuytten, M De Cuyper - Biomaterials, 2011 - Elsevier
The in vitro labelling of cultured cells with iron oxide nanoparticles (NPs) is a frequent
practice in biomedical research. To date, the potential cytotoxicity of these particles remains …

Dextran and polymer polyethylene glycol (PEG) coating reduce both 5 and 30 nm iron oxide nanoparticle cytotoxicity in 2D and 3D cell culture

M Yu, S Huang, KJ Yu, AM Clyne - International journal of molecular …, 2012 - mdpi.com
Superparamagnetic iron oxide nanoparticles are widely used in biomedical applications, yet
questions remain regarding the effect of nanoparticle size and coating on nanoparticle …

The responses of immune cells to iron oxide nanoparticles

Y Xu, JA Sherwood, KH Lackey… - Journal of Applied …, 2016 - Wiley Online Library
Immune cells play an important role in recognizing and removing foreign objects, such as
nanoparticles. Among various parameters, surface coatings of nanoparticles are the first …