The natural extracellular matrix (ECM), thanks to its specific properties (eg, collagenous
lattice, a reservoir of growth factors, ECM‐cell anchoring areas, an optimal pH and CO2) …

Decellularization is the process of removing the cellular components from tissues or organs.
It is a promising technology for obtaining a biomaterial with a highly preserved extracellular …

Reproduction of different tissues using scaffolds and materials is a major element in
regenerative medicine. The regeneration of whole organs with decellularized extracellular …

The advancement and improvement in decellularization methods can be attributed to the
increasing demand for tissues and organs for transplantation. Decellularized tissues and …

As the gap between donors and patients in need of an organ transplant continues to widen,
research in regenerative medicine seeks to provide alternative strategies for treatment. One …

The in vitro reconstruction of the extracellular matrix (ECM) is required in tissue engineering
and regenerative medicine because the ECM can regulate cell functions in vivo. For ECM …

Importance of the field: Biomimetic scaffolds and substrates of extracellular matrices (ECMs)
play an important role in the regulation of cell function and in the guidance of new tissue …

Decellularized organs and tissues are effectively utilized in a diversity of regenerative
medicine purposes, and the decellularization approaches employed differ as broadly as the …

Extracellular matrix (ECM) is a natural biomaterial scaffold that provides biochemical and
structural support to its surrounding cells, forming tissue and respective organs. These ECM …

The goal of tissue decellularization is to efficiently remove unwanted cellular components,
such as DNA and cellular debris, while retaining the complex structural and molecular milieu …