Recent advances in superparamagnetic iron oxide nanoparticles (SPIONs) for in vitro and in vivo cancer nanotheranostics

G Kandasamy, D Maity - International journal of pharmaceutics, 2015 - Elsevier
Recently superparamagnetic iron oxide nanoparticles (SPIONs) have been extensively used
in cancer therapy and diagnosis (theranostics) via magnetic targeting, magnetic resonance …

[HTML][HTML] Superparamagnetic iron oxide nanoparticles: promises for diagnosis and treatment of cancer

S Laurent, M Mahmoudi - International journal of molecular …, 2011 - ncbi.nlm.nih.gov
During the last decade, significant scientific research efforts have led to a significant growth
in understanding of cancer at the genetic, molecular, and cellular levels providing great …

[HTML][HTML] Superparamagnetic iron oxide nanoparticles (SPION): from fundamentals to state-of-the-art innovative applications for cancer therapy

T Vangijzegem, V Lecomte, I Ternad, L Van Leuven… - Pharmaceutics, 2023 - mdpi.com
Despite significant advances in cancer therapy over the years, its complex pathological
process still represents a major health challenge when seeking effective treatment and …

Superparamagnetic iron oxide nanoparticles: magnetic nanoplatforms as drug carriers

null Wahajuddin, S Arora - International journal of nanomedicine, 2012 - Taylor & Francis
A targeted drug delivery system is the need of the hour. Guiding magnetic iron oxide
nanoparticles with the help of an external magnetic field to its target is the principle behind …

[HTML][HTML] Use of superparamagnetic iron oxide nanoparticles (SPIONs) via multiple imaging modalities and modifications to reduce cytotoxicity: An educational review

NR Nelson, JD Port, MK Pandey - Journal of Nanotheranostics, 2020 - mdpi.com
The aim of the present educational review on superparamagnetic iron oxide nanoparticles
(SPIONs) is to inform and guide young scientists and students about the potential use and …

Targeted superparamagnetic iron oxide nanoparticles for early detection of cancer: Possibilities and challenges

Z Bakhtiary, AA Saei, MJ Hajipour, M Raoufi… - … , Biology and Medicine, 2016 - Elsevier
Nanomedicine, the integration of nanotechnological tools in medicine demonstrated
promising potential to revolutionize the diagnosis and treatment of various human health …

Development and characterization of magnetic iron oxide nanoparticles with a cisplatin-bearing polymer coating for targeted drug delivery

H Unterweger, R Tietze, C Janko, J Zaloga… - International journal …, 2014 - Taylor & Francis
A highly selective and efficient cancer therapy can be achieved using magnetically directed
superparamagnetic iron oxide nanoparticles (SPIONs) bearing a sufficient amount of the …

Superparamagnetic iron oxide nanoparticles (SPIONs): development, surface modification and applications in chemotherapy

M Mahmoudi, S Sant, B Wang, S Laurent… - Advanced drug delivery …, 2011 - Elsevier
At present, nanoparticles are used for various biomedical applications where they facilitate
laboratory diagnostics and therapeutics. More specifically for drug delivery purposes, the …

Superparamagnetic iron oxide nanoparticles conjugated with folic acid for dual target-specific drug delivery and MRI in cancer theranostics

Y Huang, K Mao, B Zhang, Y Zhao - Materials Science and Engineering: C, 2017 - Elsevier
Monodispersed SPIONs (superparamagnetic iron oxide nanoparticles) co-coated with PEG
and PEI polymers were prepared by an improved polyol method. To accomplish cancer …

Glioma-targeted superparamagnetic iron oxide nanoparticles as drug-carrying vehicles for theranostic effects

HL Xu, KL Mao, YP Huang, JJ Yang, J Xu, PP Chen… - Nanoscale, 2016 - pubs.rsc.org
Multifunctional nanoparticles capable of the specific delivery of therapeutics to diseased
cells and the real-time imaging of these sites have the potential to improve cancer treatment …