Mycobacterium tuberculosis remains one of the most pernicious of human pathogens.
Current vaccines are ineffective, and drugs, although efficacious, require prolonged …

Mycobacterium tuberculosis is a highly efficient pathogen, killing millions of infected people
annually. The capacity of M. tuberculosis to survive and cause disease is strongly correlated …

The interaction between Mycobacterium tuberculosis and its host cell is highly complex and
extremely intimate. Were it not for the disease, one might regard this interaction at the …

Mycobacterium tuberculosis is an extremely successful pathogen that demonstrates the
capacity to modulate its host both at the cellular and tissue levels. At the cellular level, the …

Mycobacterium tuberculosis, the causative agent of tuberculosis, has infected humans for
millennia. M. tuberculosis is well adapted to establish infection, persist in the face of the host …

Mycobacterium tuberculosis is a highly successful pathogen that parasitizes the
macrophages of its host. Its success can be attributed directly to its ability to manipulate the …

The intimate and persistent connection between Mycobacterium tuberculosis and its human
host suggests that the pathogen has evolved extensive mechanisms to evade eradication by …

Mycobacterium tuberculosis (Mtb) is highly immunogenic and appears to have evolved to
preserve its antigenicity. The retention of antigenicity is important to the maintenance of a …

Metabolism is a widely recognized facet of all host–pathogen interactions. Knowledge of its
roles in pathogenesis, however, remains comparatively incomplete. Existing studies have …

Mycobacterium tuberculosis remains a leading cause of morbidity and mortality worldwide.
Advances reported at a recent international meeting highlight insights and controversies in …