Angiogenesis research in the past two decades has contributed significantly towards
understanding the molecular pathophysiology of cancer progression and inspired target …

Activation of the tumor and stromal cell-driven angiogenic program is one of the first
requirements in the tumor ecosystem for growth and dissemination. The understanding of …

Advances in molecular biology have permitted the characterisation of mechanisms
underlying angiogenesis. Angiogenesis is a crucial process in tumour pathogenesis as it …

Angiogenesis is the process through which novel blood vessels are formed from pre-existing
ones and it is involved in both physiological and pathological processes of the body …

Angiogenesis: a process of generation of new blood vessels has been proved to be
necessary for sustained tumor growth and cancer progression. Inhibiting angiogenesis …

A vast amount of data shows that angiogenesis has a pivotal role in tumor growth,
progression, invasiveness and metastasis. This is a complex process involving essential …

The establishment of a functional, integrated vascular system is instrumental for tissue
growth and homeostasis. Without blood vessels no adequate nutrition and oxygen would be …

Primary solid tumors originate close to pre-existing tissue vasculature, initially growing along
such tissue blood vessels, and this phenomenon is important for the metastatic potential …

Since 2004, four antiangiogenic drugs have been approved for clinical use in patients with
advanced solid cancers, on the basis of their capacity to improve survival in phase III clinical …

Angiogenesis, or the formation of new capillary blood vessels, occurs primarily during
human development and reproduction; however, aberrant regulation of angiogenesis is also …