Sickle cell disease (SCD) is an autosomal recessive disorder that results in hemolytic
anemia related to abnormal hemoglobin and erythrocyte levels. SCD is characterized by …

Sickle cell disease (SCD) is a group of inherited disorders caused by a mutation of the
hemoglobin gene, resulting in the formation of abnormal, sickle-shaped red blood cells. It is …

Sickle cell disease (SCD) is an autosomal recessive disorder that is characterized by
abnormal “sickle-shaped” erythrocytes. Because of their shape, these erythrocytes are more …

The bony skeleton of the patient with sickle cell disease is a frequent target of the
consequences of sickling. Bone marrow necrosis, bone infarcts, osteomyelitis, and aseptic …

Sickle cell anaemia is an autosomal recessive genetic condition producing abnormal
haemoglobin HbS molecules that result in stiff and sticky red blood cells leading to …

Patients with sickle-cell anemia and related hemoglobinopathies may frequently have bone
pain and limitation of motion resulting from infection or vascular occlusion which can lead to …

Sickle cell disease (SCD) is an inherited disorder of abnormal haemoglobin commonly
encountered in the West African sub-region. It has varied osteoarticular and non-osseous …

In sickle cell disease, various disturbances commonly affect the bones and joints. Vaso-
occlusive events in blood vessels that traverse the bones cause acute and chronic morbidity …

Bone involvement is the commonest clinical manifestation of sickle cell disease both in the
acute setting such as painful vaso‐occlusive crises, and as a source of chronic, progressive …

Osteonecrosis secondary to sickle cell anemia and its genetic variants has many
presentations depending on the age of onset and the extent of femoral head involvement …