New vessel formation inside the arterial wall and atherosclerotic plaques plays a critical role
in pathogenesis of heart attacks and strokes. The 2 known mechanisms resulting in the …

Endothelial dysfunction and inflammation of the arterial wall continuously drive the
development of atherosclerosis. Details regarding the sequential involvement of different …

Inflammation plays a key role in the pathogenesis of atherosclerosis. The more we discover
about the molecular pathways involved in atherosclerosis, the more we perceive the …

Atherosclerosis is one of the leading causes of death and disability worldwide. It is a
complex disease characterized by lipid accumulation within the arterial wall, inflammation …

It is now clear that the monocyte/macrophage has a crucial role in the development of
atherosclerosis. This cell appears to be involved in all stages of atherosclerotic plaque …

Chronic inflammation drives atherosclerosis, the leading cause of cardiovascular disease.
Over the past two decades, data have emerged showing that immune cells are involved in …

The activation of endothelial cells at atherosclerotic lesion–prone sites in the arterial tree
results in the up-regulation of cell adhesion molecules and chemokines, which mediate the …

Despite improvements in interventional and pharmacological therapy of atherosclerotic
disease, it is still the leading cause of death in the developed world. Hence, there is a need …

The involvement of the bloodborne monocyte in phenomena related to vascular interactions,
including wound healing and atherosclerosis, has been well recognised for several …

Monocytes play a key role in cardiovascular disease (CVD) as their influx into the vessel
wall is necessary for the development of an atherosclerotic plaque. Monocytes are, however …