Most multicellular organisms have a major body cavity containing vital organs. This cavity is
lined by a mucosa-like serosal surface and filled with serous fluid which suspends many …

Recruitment of bone marrow derived monocytes via bloodstream and their subsequent
conversion to CX3CR1+ macrophages in response to intestinal injury is dependent on …

Post-surgical adhesions are internal scar tissue and a major health and economic burden.
Adhesions affect and involve the peritoneal lining of the abdominal cavity, which consists of …

Post-operative adhesions are a leading cause of abdominal surgery-associated morbidity.
Exposed fibrin clots on the damaged peritoneum, in which the mesothelial barrier is …

A key feature of inflammation is the timely recruitment of leukocytes, including monocytes,
from blood into tissues, the latter maturing into macrophages over a period of 2–3 days …

Peritoneal adhesions are pathological fibroses that ensnare organs after abdominal surgery.
This dense connective tissue can cause small bowel obstruction, female infertility, and …

Severe trauma is accompanied by a profound activation of the immune system. Patients with
polytrauma develop systemic inflammatory response syndrome (SIRS) and often sepsis …

The peritoneum defines a confined microenvironment, which is stable under normal
conditions, but is exposed to the damaging effect of infections, surgical injuries, and other …

INTRODUCTION Most multicellular organisms have a major body cavity that harbors
immune cells. In primordial species such as the purple sea urchin, these cells—called …

Peritoneal adhesions commonly occur after abdominal or pelvic surgery. These scars join
internal organs to each other or to the cavity wall and can present with abdominal or pelvic …