Emerging roles of extracellular vesicles in neurodegenerative disorders

Y You, T Ikezu - Neurobiology of Disease, 2019 - Elsevier
Extracellular vesicles (EVs) are heterogeneous cell-derived membranous vesicles which
carry a large diversity of molecules such as proteins and RNA species. They are now …

Emerging roles of extracellular vesicles in the central nervous system: Physiology, pathology, and therapeutic perspectives

Y Gassama, A Favereaux - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Extracellular vesicles or EVs are secreted by most, if not all, eukaryote cell types and
recaptured by neighboring or distant cells. Their cargo, composed of a vast diversity of …

Research progress on the role of extracellular vesicles in neurodegenerative diseases

Z Li, X Wang, X Wang, X Yi, YK Wong, J Wu… - Translational …, 2023 - Springer
Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease,
amyotrophic lateral sclerosis, and Huntington's disease, affect millions of people worldwide …

Extracellular vesicles, from the pathogenesis to the therapy of neurodegenerative diseases

X Xia, Y Wang, JC Zheng - Translational Neurodegeneration, 2022 - Springer
Extracellular vesicles (EVs) are small bilipid layer-enclosed vesicles that can be secreted by
all tested types of brain cells. Being a key intercellular communicator, EVs have emerged as …

The role of extracellular vesicles in the progression of neurodegenerative disease and cancer

KM Candelario, DA Steindler - Trends in molecular medicine, 2014 - cell.com
Extracellular vesicles (EVs) are released from many cell types, including normal and
pathological cells, and range from 30 to 1000nm in size. Once thought to be a mechanism …

Role of extracellular vesicles in neurodegenerative diseases

Y Xiao, SK Wang, Y Zhang, A Rostami, A Kenkare… - Progress in …, 2021 - Elsevier
Extracellular vesicles (EVs) are heterogeneous cell-derived membranous structures that
arise from the endosome system or directly detach from the plasma membrane. In recent …

Potential of extracellular vesicles in neurodegenerative diseases: diagnostic and therapeutic indications

M Izadpanah, A Seddigh, S Ebrahimi Barough… - Journal of Molecular …, 2018 - Springer
Extracellular vesicles (EVs) are membrane-bound vesicles, including exosomes and
microvesicles. EVs are nanometer sized, found in physiological fluids such as urine, blood …

Extracellular vesicles in neurodegenerative diseases: A systematic review

A Raghav, M Singh, GB Jeong, R Giri… - Frontiers in molecular …, 2022 - frontiersin.org
Introduction Extracellular vesicles (EVs) are known to have a significant role in the central
nervous system (CNS) and neurodegenerative disease. Methods PubMed, Scopus, ISI Web …

Emerging role of extracellular vesicles in intercellular communication in the brain: Implications for neurodegenerative diseases and therapeutics

S Sarkar, S Patranabis - Cell Biochemistry and Biophysics, 2024 - Springer
Extracellular vesicles (EVs) are minute lipid-bilayer sacs discharged by cells, encompassing
a diverse array of proteins, nucleic acids, and lipids. The identification of EVs as pivotal …

Extracellular vesicles in neurodegenerative disease—pathogenesis to biomarkers

AG Thompson, E Gray, SM Heman-Ackah… - Nature Reviews …, 2016 - nature.com
To develop effective disease-modifying therapies for neurodegenerative diseases, reliable
markers of diagnosis, disease activity and progression are a research priority. The fact that …