Age-linked changes in the activity of enzymes of the tricarboxylate cycle and lipid oxidation, and of carnitine content, in muscles of the rat
RG Hansford, F Castro - Mechanisms of ageing and development, 1982 - Elsevier
The activities of citrate synthase, NAD-isocitrate dehydrogenase and 2-oxoglutarate
dehydrogenase were measured in homogenates of soleus, diaphragm and heart muscles of …
dehydrogenase were measured in homogenates of soleus, diaphragm and heart muscles of …
Lipid oxidation by heart mitochondria from young adult and senescent rats
RG Hansford - Biochemical Journal, 1978 - portlandpress.com
1. State-3 (ie ADP-stimulated) rates of O2 uptake with palmitoylcarnitine, palmitoyl-CoA plus
carnitine, pyruvate plus malonate plus carnitine and octanoate as respiratory substrate were …
carnitine, pyruvate plus malonate plus carnitine and octanoate as respiratory substrate were …
[引用][C] Fatty acid oxidation and some participating enzymes in animal organs
AMT Beenakkers, JH Dewaide, PT Henderson… - Comparative …, 1967 - Elsevier
1. The activity of an enzyme of the fatty acid oxidation cycle is compared to the activity of
both short-and long-chain carnitine acyltransferase in organs of rat, pigeon and locust. 2. 2 …
both short-and long-chain carnitine acyltransferase in organs of rat, pigeon and locust. 2. 2 …
[引用][C] Carnitine and fatty acid oxidation in mitochondria of various organs
M Klingenberg, C Bode - Biochimica et Biophysica Acta (BBA)-Specialized …, 1964 - Elsevier
In the earlier work on the oxidation of fatty acids in vitro only fatty acids of short chain length
could be utilized with an appreciable activity xs. The stimulating effect of carnitine on the …
could be utilized with an appreciable activity xs. The stimulating effect of carnitine on the …
Carnitine-acylcarnitine translocase activity in cardiac mitochondria from aged rats: the effect of acetyl-L-carnitine
G Paradies, FM Ruggiero, G Petrosillo… - Mechanisms of ageing …, 1995 - Elsevier
Age-related changes in mitochondrial fatty acids metabolism may underlie the progressive
decline in cardiac function. The effect of aging and acute treatment with acetyl-L-carnitine on …
decline in cardiac function. The effect of aging and acute treatment with acetyl-L-carnitine on …
[引用][C] The Effect of Aging and Acetyl‐L‐carnitine on the Function and on the Lipid Composition of Rat Heart Mitochondriaa
G Paradies, FM Ruggiero, G Petrosillo… - Annals of the New …, 1994 - Wiley Online Library
Aging is associated with alterations of various aspects of cell functions. It is a common
observation that aged animals tend to be less energetic. The molecular basis of this age …
observation that aged animals tend to be less energetic. The molecular basis of this age …
[引用][C] Carnitine-coenzyme A transacetylase in mitochondria from various organs
AMT Beenakkers, M Klingenberg - … BBA)-Specialized Section on Lipids and …, 1964 - Elsevier
Thus a participation of carnitine in metabolism by forming another type of" activated" acetic
acid was directly demonstrated. On the other hand carnitine had been shown to be a …
acid was directly demonstrated. On the other hand carnitine had been shown to be a …
Mitochondrial metabolism and substrate competition in the aging Fischer rat heart
JB McMillin, GE Taffet, H Taegtmeyer… - Cardiovascular …, 1993 - academic.oup.com
Objective: The objective was to examine mitochondrial oxidative metabolism of long chain
fatty acids and to compare it with glucose uptake and the generation of pressure-volume …
fatty acids and to compare it with glucose uptake and the generation of pressure-volume …
Carnitine and brown adipose tissue metabolism in the rat during development
P Hahn, J Skala - Biochemical Journal, 1972 - portlandpress.com
1. The content of carnitine, acylcarnitine and total acid soluble carnitine in brown adipose
tissue of rats increases rapidly after birth, attaining a peak on about day 10 and then …
tissue of rats increases rapidly after birth, attaining a peak on about day 10 and then …
Fatty acid oxidation by isolated perfused working hearts of aged rats.
GM Abu-Erreish, JR Neely… - American Journal …, 1977 - journals.physiology.org
It has been reported that mitochondria isolated from hearts of old rats have lower respiratory
activity than mitochondria from young rats. In order to determine the physiological correlates …
activity than mitochondria from young rats. In order to determine the physiological correlates …
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