[HTML][HTML] Peroxisome proliferator-activated receptors as targets to treat non-alcoholic fatty liver disease

V Souza-Mello - World journal of hepatology, 2015 - ncbi.nlm.nih.gov
Lately, the world has faced tremendous progress in the understanding of non-alcoholic fatty
liver disease (NAFLD) pathogenesis due to rising obesity rates. Peroxisome proliferator …

Revealing the role of peroxisome proliferator-activated receptor β/δ in nonalcoholic fatty liver disease

M Zarei, D Aguilar-Recarte, X Palomer… - Metabolism, 2021 - Elsevier
Nonalcoholic fatty liver disease (NAFLD), a form of chronic liver disease that occurs in
individuals with no significant alcohol abuse, has become an increasing concern for global …

[HTML][HTML] Peroxisome proliferator-activated receptors and their novel ligands as candidates for the treatment of non-alcoholic fatty liver disease

A Fougerat, A Montagner, N Loiseau, H Guillou… - Cells, 2020 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a major health issue worldwide, frequently
associated with obesity and type 2 diabetes. Steatosis is the initial stage of the disease …

Peroxisome proliferator-activated receptors and their agonists in nonalcoholic fatty liver disease

NS Choudhary, N Kumar, A Duseja - Journal of Clinical and Experimental …, 2019 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases
worldwide. In addition to the liver-related morbidity and mortality, NAFLD is now also …

PPARs and nonalcoholic fatty liver disease

KHH Liss, BN Finck - Biochimie, 2017 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) encompasses a range of liver pathology ranging
from simple steatosis to varying degrees of inflammation, hepatocyte injury and fibrosis …

PPAR-γ signaling in nonalcoholic fatty liver disease: Pathogenesis and therapeutic targets

H Chen, H Tan, J Wan, Y Zeng, J Wang… - Pharmacology & …, 2023 - Elsevier
Non-alcoholic fatty liver disease (NAFLD), currently the leading cause of global chronic liver
disease, has emerged as a major public health problem, more efficient therapeutics of which …

Roles of PPARs in NAFLD: potential therapeutic targets

A Tailleux, K Wouters, B Staels - … et Biophysica Acta (BBA)-Molecular and …, 2012 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a liver pathology with increasing prevalence
due to the obesity epidemic. Hence, NAFLD represents a rising threat to public health …

[HTML][HTML] Role of peroxisome proliferators-activated receptors in the pathogenesis and treatment of nonalcoholic fatty liver disease

ER Kallwitz, A McLachlan, SJ Cotler - World journal of …, 2008 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is highly prevalent and can result in nonalcoholic
steatohepatitis (NASH) and progressive liver disease including cirrhosis and hepatocellular …

A role of peroxisome proliferator‐activated receptor γ in non‐alcoholic fatty liver disease

J Skat‐Rørdam, D Højland Ipsen… - Basic & clinical …, 2019 - Wiley Online Library
Non‐alcoholic fatty liver disease is becoming a major health burden, as prevalence
increases and there are no approved treatment options. Thiazolidinediones target the …

[HTML][HTML] Insights into the Role of PPARβ/δ in NAFLD

J Chen, A Montagner, NS Tan, W Wahli - International journal of …, 2018 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a major health issue in developed countries.
Although usually associated with obesity, NAFLD is also diagnosed in individuals with low …