Understanding the molecular epidemiology of tuberculosis (TB) and mutations in genes
associated with drug resistance may contribute to the development of appropriate …

High incidence rates of isoniazid-, rifampin-, and multiple-drug-resistant tuberculosis have
been reported in countries of the former Soviet Union (FSU). Genotypic (unlike phenotypic) …

Abstract Background Drug resistance in Mycobacterium tuberculosis is associated with
chromosomal mutations in selected genes. These mutations can be screened for an early …

To characterize the genetic basis of drug resistance in Mycobacterium tuberculosis in Latvia,
mutations involved in rifampin (rpoB gene) and isoniazid (katG gene) resistance in DNA …

Abstract Objectives Three Mycobacterium tuberculosis genetic loci—rpoB and katG genes
and the fabG1 (mabA)–inhA operon promoter region—were studied to reveal the mutations …

ABSTRACT A total of 105 rifampin (RMP)-and/or isoniazid (INH)-resistant strains of
Mycobacterium tuberculosis isolated from different parts of Poland in 2000 were screened …

OBJECTIVE: To analyse possible associations of specific mutations conferring rifampicin
(RMP) and isoniazid (INH) resistance with Beijing and non Beijing genotype strains of …

In order to characterize mutations causing rifampicin and isoniazid resistance of M.
tuberculosis in Syria, 69 rifampicin resistant (Rifr) and 72 isoniazid resistant (Inhr) isolates …

SETTING: Modern molecular methods help us to understand the transmission and
epidemiology of Mycobacterium tuberculosis. OBJECTIVE: To analyse the molecular …

Kazakhstan is one of the 14 countries with a high rate of morbidity due to multidrugresistant
tuberculosis (MDR TB) in WHO European region. The aim of our study was to characterize …