Nanoparticle size is a critical physicochemical determinant of the human blood plasma corona: a comprehensive quantitative proteomic analysis
S Tenzer, D Docter, S Rosfa, A Wlodarski, J Kuharev… - ACS …, 2011 - ACS Publications
In biological fluids, proteins associate with nanoparticles, leading to a protein “corona”
defining the biological identity of the particle. However, a comprehensive knowledge of …
defining the biological identity of the particle. However, a comprehensive knowledge of …
Effect of surface chemistry and morphology of gold nanoparticle on the structure and activity of common blood proteins
Keeping the native structure and activity of proteins, while adsorbed onto a nanoparticle
surface, is one of the pre-requisites for the real biological applications of nanoparticles …
surface, is one of the pre-requisites for the real biological applications of nanoparticles …
Relating the composition and interface interactions in the hard corona of gold nanoparticles to the induced response mechanisms in living cells
Understanding the formation of the intracellular protein corona of nanoparticles is essential
for a wide range of bio-and nanomedical applications. The innermost layer of the protein …
for a wide range of bio-and nanomedical applications. The innermost layer of the protein …
Nanoparticle-protein corona complex: understanding multiple interactions between environmental factors, corona formation, and biological activity
The surfaces of pristine nanoparticles become rapidly coated by proteins in biological fluids,
forming the so-called protein corona. The corona modifies key physicochemical …
forming the so-called protein corona. The corona modifies key physicochemical …
An analysis of the binding function and structural organization of the protein corona
Blood proteins adsorb onto the surface of nanoparticles after intravenous injection to form a
protein corona. The underlying organization and binding function of these adsorbed proteins …
protein corona. The underlying organization and binding function of these adsorbed proteins …
Cellular binding of anionic nanoparticles is inhibited by serum proteins independent of nanoparticle composition
Nanoparticles used in biological applications encounter a complex mixture of extracellular
proteins. Adsorption of these proteins on the nanoparticle surface results in the formation of …
proteins. Adsorption of these proteins on the nanoparticle surface results in the formation of …
Nanoparticle–protein corona complexes govern the biological fates and functions of nanoparticles
Upon contact with plasma or other protein-containing biological fluids, the surface of
nanoparticles is immediately decorated with proteins forming a biologically active protein …
nanoparticles is immediately decorated with proteins forming a biologically active protein …
The influence of shape and charge on protein corona composition in common gold nanostructures
T Bewersdorff, EA Glitscher, J Bergueiro… - Materials Science and …, 2020 - Elsevier
With increasing importance of gold nanoparticles (AuNPs) in the medical field, the
understanding of their interactions in biological environments is essential. It is known that …
understanding of their interactions in biological environments is essential. It is known that …
Gold nanoparticle should understand protein corona for being a clinical nanomaterial
Gold nanoparticles (AuNPs) have attracted great attention in biomedical fields due to their
unique properties. However, there are few reports on clinical trial of these nanoparticles. In …
unique properties. However, there are few reports on clinical trial of these nanoparticles. In …
Protein corona mediated uptake and cytotoxicity of silver nanoparticles in mouse embryonic fibroblast
Medical applications of nanoparticles (NPs) require understanding of their interactions with
living systems in order to control their physiological response, such as cellular uptake and …
living systems in order to control their physiological response, such as cellular uptake and …