Calcineurin is a highly conserved Ca2+/calmodulin-dependent serine/threonine-specific
protein phosphatase that orchestrates cellular Ca2+ signaling responses. In Cryptococcus …

Cryptococcus neoformans survives host temperature and regulates cell wall integrity via a
calcium-dependent phosphatase, calcineurin. However, downstream effectors of C …

Calcineurin governs stress survival, sexual differentiation, and virulence of the human fungal
pathogen Cryptococcus neoformans. Calcineurin is activated by increased Ca2+ levels …

Calcineurin is a calcium-calmodulin-activated serine/threonine-specific phosphatase that
operates during cellular responses to stress and plays a prominent role in transcriptional …

Ca2+, as a second messenger in cells, enables organisms to adapt to different
environmental stresses by rapidly sensing and responding to external stimuli. In recent …

The protein phosphatase calcineurin is an important mediator connecting calcium‐
dependent signalling to various cellular responses in multiple organisms. In fungi …

Abstract The Ca2+/calmodulin-dependent protein phosphatase calcineurin orchestrates
sexual reproduction, stress responses, and virulence via branched downstream pathways in …

Calcineurin is a phosphoprotein phosphatase devoted to the transduction of Ca 2+-signals
in eukaryotes. In the human pathogen Candida albicans, calcineurin function is required for …

In Saccharomyces cerevisiae, the Ca 2+/calmodulin-dependent protein phosphatase,
calcineurin, is activated by specific environmental conditions, including exposure to Ca 2+ …

The function of calcium as a signaling molecule is conserved in eukaryotes from fungi to
humans. Previous studies have identified the calcium-activated phosphatase calcineurin as …