Like all viruses, hepatitis B virus (HBV) replication and pathogenesis depends on the critical
interplay between viral and host factors. In this review, we will focus on the recent progress …

Highlights•HBV HBx is required for virus replication.•Required HBx function (s) may vary
with the stage of chronic HBV infection.•HBx binding to DDB1 may impact several DDB1 …

About 250 million people worldwide are chronically infected with Hepatitis B virus (HBV),
contributing to a large burden on public health. Despite the existence of vaccines and …

The efficient replication of hepatitis B virus (HBV) requires the HBV regulatory hepatitis B
virus X (HBx) protein. The exact contributions of HBx are not fully understood, in part …

Hepatitis B virus (HBV) poses a threat to global public health mainly because of
complications of HBV‐related chronic liver disease. HBV exhibits a narrow host range …

Hepatitis B virus (HBV) is a hepatotropic virus and an important human pathogen. There are
an estimated 296 million people in the world that are chronically infected by this virus, and …

BACKGROUND & AIMS: The molecular biology of hepatitis B virus (HBV) has been
extensively studied but the exact role of the hepatitis BX protein (HBx) in the context of …

Hepatitis B virus is considered one of the most significant environmental carcinogens in
humans. Because the mechanisms of HBV replication and the development of …

As obligate intracellular parasites, viruses need a host cell to provide a milieu favorable to
viral replication. Consequently, viruses often adopt mechanisms to subvert host cellular …

Hepatitis B, a global health concern caused by the hepatitis B virus (HBV), infects nearly 2
billion individuals worldwide, as reported by the World Health Organization (WHO). HBV, a …