Background Esophageal squamous cell carcinoma (ESCC) is one of the most common
causes of cancer mortality in the gastrointestinal tract. Promoter hypermethylation of tumor …

Abstract Background Glutathione peroxidase 3 (GPX3) provides critical protection against
reactive oxygen species (ROS) in cells. Downregulation of GPX3 may contribute to …

Background/aims Accumulating evidence has identified transcriptional silencing by aberrant
methylation of CpG islands as a potential mechanism for the inactivation of tumor …

Aim: This study investigated the association between GPX3 methylation and gastric cancer
(GC), and explored its prognostic value in patients undergoing radical gastrectomy …

Stomach cancer is the second largest cause of cancer‐related mortality globally, and it
continues to be a reason for worry today. Inhalation of the stomach cancer risk factor H …

Abstract Glutathione peroxidase 3 (GPX3) has an important function of scavenging
hydrogen peroxide and preventing cancer. The purpose of this meta-analysis was to …

Background Chaoshan region, a littoral area of Guangdong province in southern China, has
a high incidence of esophageal squamous cell carcinoma (ESCC). At present, the prognosis …

Background: This study aimed at examining the association of gene silencing and promoter
methylation of glutathione peroxidase 1 (GPX1) and glutathione peroxidase 3 (GPX3) in …

To identify novel methylation-silenced genes in gastric cancer, we carried out a genome-
wide search for genes that are up-regulated after treatment with the demethylating agent, 5 …

AIM: To study the mechanisms responsible for inactivation of a novel esophageal cancer
related gene 4 (ECRG4) in esophageal squamous cell carcinoma (ESCC). METHODS: A …