Organ fibrosis represents a vital health threat that substantially contributes to yearly mortality
rates. While a considerable amount of research has been conducted on fibrosis, these …

Background Fibrosis in most organs has proven to be an critical factor related to high risk of
morbidity and mortality, but an adequate assessment of fibrosis severity is still challenging …

Fibrosis, a progressive accumulation of extracellular matrix components, encompasses a
wide spectrum of distinct organs, and accounts for an increasing burden of morbidity and …

Fibroproliferative diseases of organs are poorly understood and generally lack effective anti-
fibrotic treatments. Our goal was to identify the key regulatory factors in pathologic fibrosis …

Fibrosis, the excessive accumulation of extracellular matrix, is a major global healthcare
burden. Despite major advances in our understanding of the mechanisms regulating …

Fibrosis, or the accumulation of extracellular matrix molecules that make up scar tissue, is a
common feature of chronic tissue injury. Pulmonary fibrosis, renal fibrosis, and hepatic …

Fibrosis can affect any organ and is responsible for up to 45% of all deaths in the
industrialized world. It has long been thought to be relentlessly progressive and irreversible …

Fibrosis, or tissue scarring, develops as a pathological deviation from the physiological
wound healing response and can occur in various organs such as the heart, lung, liver …

Fibrosis, a complex process of abnormal tissue healing which inevitably leads to loss of
physiological organ structure and function, is a worldwide leading cause of death. Despite a …

Fibrosis is a prevalent and detrimental condition associated with various diseases with a
high impact on global morbidity and mortality rates. Despite its diverse causes and affected …