The insulin receptor (INSR), which is an indispensable component of the insulin-signalling
pathway, could be a plausible candidate gene for polycystic ovary syndrome (PCOS). This …

Background Polycystic ovary syndrome (PCOS) is a complex disease having both genetic
and environmental components. Candidate genes with insulin metabolism have been …

Objective This study is designed to determine whether an association exists between single
nucleotide polymorphism (SNP) variant rs2252673 of insulin receptor (INSR) gene and …

Polycystic ovary syndrome (PCOS) is the most common gynecological endocrine disorder.
The genetic background is believed to play a crucial role in the pathogenesis of PCOS. In …

OBJECTIVE: To investigate several single nucleotide polymorphisms (SNPs) in the insulin
receptor (INSR) gene that have significant associations with pathogenesis of polycystic …

OBJECTIVE: To evaluate association with polycystic ovary syndrome (PCOS) of 295 variants
in 39 genes central to metabolic insulin signaling and glycogen synthase kinase 3β (GSK …

Background Insulin and its receptor (INSR) have been implicated in the etiology of the
polycystic ovarian syndrome (PCOS). Here, we investigate the association between INSR …

To investigate the association of single-nucleotide polymorphisms (SNPs) in exon 17 of the
insulin receptor (INSR) gene with insulin resistance and INSR β-subunit expression in …

Aim Recently, the roles of insulin receptor (INSR) and insulin receptor substrate (IRS)
polymorphisms in polycystic ovary syndrome (PCOS) have been extensively studied, with …

OBJECTIVE: To examine whether the insulin receptor (INSR) gene contributes to genetic
susceptibility to the polycystic ovary syndrome (PCOS). DESIGN: Case–control study …