Introduction: Obesity is compounded by a neurobiology that is resistant to weight loss.
Therefore, the development of pharmacotherapies to address the pathology underlying the …

Introduction: Obesity is a rapidly increasing global health problem. The rates of obesity have
tripled over the past three decades and are predicted to rise even further. The need for safe …

BACKGROUND Although pharmacotherapy is not the cornerstone of obesity treatment, it is
a valuable tool that could be considered for patients who have not had adequate benefit …

Abstract Purpose of Review Obesity is a global health crisis with detrimental effects on all
organ systems leading to worsening disease state and rising costs of care. Persons with …

Available anti-obesity pharmacotherapy options remain very limited and development of
more effective drugs has become a priority. The potential strategies to achieve weight loss …

The prevalence of obesity has increased worldwide, and approximately 25%–35% of the
adult population is obese in some countries. The excess of body fat is associated with …

Introduction: The discovery of new antiobesity agents has attracted considerable interest
over the past decade, but many of the investigational agents that have advanced into human …

The unabated rise in the prevalence of obesity is a challenge for global health care systems.
Efforts to reverse this trend by dietary or behavioral counseling have not been successful …

Pharmacotherapy has a role in obesity management when combined with diet, physical
activity, and behavior modification. Currently available therapies are safe when used …

Public health initiatives focused on obesity prevention and lifestyle intervention programmes
for patients with obesity have struggled to contain the obesity epidemic to date. In recent …