Prophylactic human papillomavirus vaccines

DR Lowy, JT Schiller - The Journal of clinical investigation, 2006 - Am Soc Clin Investig
Human papillomavirus (HPV) infection causes virtually all cases of cervical cancer, the
second most common cause of death from cancer among women worldwide. This Review …

Developing vaccines against minor capsid antigen L2 to prevent papillomavirus infection

B Karanam, S Jagu, WK Huh… - Immunology and cell …, 2009 - Wiley Online Library
A subset of human papillomavirus (HPV) genotypes is responsible for∼ 5% of all cancer
deaths globally, and uterine cervical carcinoma accounts for the majority of these cases. The …

An update on human papilloma virus vaccines: history, types, protection, and efficacy

Z Yousefi, H Aria, F Ghaedrahmati, T Bakhtiari… - Frontiers in …, 2022 - frontiersin.org
Human papillomavirus (HPV) is the most common sexually transmitted agent worldwide.
Early prevention with HPV vaccination is a safe and effective method against this disease …

A review of clinical trials of human papillomavirus prophylactic vaccines

JT Schiller, X Castellsagué, SM Garland - Vaccine, 2012 - Elsevier
End of study analyses of the phase III trials of prophylactic human papillomavirus (HPV)
virus-like particle (VLP) vaccines in young women are now largely completed. Two distinct …

Therapeutic human papillomavirus vaccines: current clinical trials and future directions

CF Hung, B Ma, A Monie, SW Tsen… - Expert opinion on …, 2008 - Taylor & Francis
Background: Cervical cancer is the second largest cause of cancer deaths in women
worldwide. It is now evident that persistent infection with high-risk human papillomavirus …

HPV vaccines to prevent cervical cancer and genital warts: an update

C Dochez, JJ Bogers, R Verhelst, H Rees - Vaccine, 2014 - Elsevier
Cervical cancer is an important public health problem worldwide, and especially in
developing countries. The link between cervical cancer and oncogenic human …

Chapter 16: Prophylactic human papillomavirus vaccines

DR Lowy, IH Frazer - JNCI Monographs, 2003 - academic.oup.com
Candidate prophylactic vaccines based on papillomavirus L1 virus-like particles (VLPs) are
currently in human clinical trials. The main long-term goal of the vaccine is to reduce the …

Developments in L2-based human papillomavirus (HPV) vaccines

C Schellenbacher, RBS Roden, R Kirnbauer - Virus research, 2017 - Elsevier
Infections with sexually transmitted high-risk Human Papillomavirus (hrHPV), of which there
are at least 15 genotypes, are responsible for a tremendous disease burden by causing …

Correlating immunity with protection for HPV infection

I Frazer - International Journal of Infectious Diseases, 2007 - Elsevier
BACKGROUND: Cervical cancer is one of the most common types of cancer in women and
is largely attributable to persistent infection with high-oncogenic risk human papillomavirus …

Recent developments in human papillomavirus (HPV) vaccinology

AL Williamson - Viruses, 2023 - mdpi.com
Human papillomavirus (HPV) is causally associated with 5% of cancers, including cancers
of the cervix, penis, vulva, vagina, anus and oropharynx. The most carcinogenic HPV is HPV …