Cytokine networks in neuroinflammation

B Becher, S Spath, J Goverman - Nature Reviews Immunology, 2017 - nature.com
Cytokines provide cells with the ability to communicate with one another and orchestrate
complex multicellular behaviour. There is an emerging understanding of the role that …

Neuro-immune crosstalk in CNS diseases

M Kerschensteiner, E Meinl, R Hohlfeld - Neuroscience, 2009 - Elsevier
Immune cells infiltrate the CNS in many neurological diseases with a primary or secondary
inflammatory component. In the CNS, immune cells employ shared mediators to promote …

Cross-talk of the CNS with immune cells and functions in health and disease

A Matejuk, AA Vandenbark, H Offner - Frontiers in neurology, 2021 - frontiersin.org
The immune system's role is much more than merely recognizing self vs. non-self and
involves maintaining homeostasis and integrity of the organism starting from early …

[HTML][HTML] Neuroinflammation: ways in which the immune system affects the brain

RM Ransohoff, D Schafer, A Vincent, NE Blachère… - …, 2015 - Elsevier
Neuroinflammation is the response of the central nervous system (CNS) to disturbed
homeostasis and typifies all neurological diseases. The main reactive components of the …

The role of peripheral immune cells in the CNS in steady state and disease

M Prinz, J Priller - Nature neuroscience, 2017 - nature.com
The CNS is protected by the immune system, including cells that reside directly within the
CNS and help to ensure proper neural function, as well as cells that traffic into the CNS with …

The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases

F Zipp, O Aktas - Trends in neurosciences, 2006 - cell.com
Classical knowledge distinguishes between inflammatory and non-inflammatory diseases of
the brain. Either the immune system acts on the CNS and initiates a damage cascade, as in …

Neuroinflammation: an integrating overview of reactive‐Neuroimmune cell interactions in health and disease

R Kölliker-Frers, L Udovin… - Mediators of …, 2021 - Wiley Online Library
The concept of central nervous system (CNS) inflammation has evolved over the last
decades. Neuroinflammation is the response of reactive CNS components to altered …

How the immune system shapes neurodegenerative diseases

HD Mason, DB McGavern - Trends in neurosciences, 2022 - cell.com
Neurodegenerative diseases are a major cause of death and disability worldwide and are
influenced by many factors including age, genetics, and injuries. While these diseases are …

An inflammation-centric view of neurological disease: beyond the neuron

SD Skaper, L Facci, M Zusso, P Giusti - Frontiers in cellular …, 2018 - frontiersin.org
Inflammation is a complex biological response fundamental to how the body deals with
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …

Connecting cytokines and brain A review of current issues

N Quan, M Herkenham - Histology and histopathology, 2002 - digitum.um.es
Cytokines have been a multi-disciplinary research focus for over 2 decades. To date, there
have been more than 15000 articles published concerning the relationship between …