Superoxide dismutase induces G1‐phase cell cycle arrest by down‐regulated expression of Cdk‐2 and cyclin‐E in murine sarcoma S180 tumor cells
D Liu, A Liu - Cell Biochemistry and Function, 2013 - Wiley Online Library
As an efficient reactive oxygen species–scavenging enzyme, superoxide dismutase (SOD)
has been shown to inhibit tumor growth and interfere with motility and invasiveness of …
has been shown to inhibit tumor growth and interfere with motility and invasiveness of …
[HTML][HTML] IFNγ-mediated inhibition of cell proliferation through increased PKCδ-induced overexpression of EC-SOD
YJ Jeon, H Yoo, BH Kim, YS Lee, B Jeon, SS Kim… - BMB …, 2012 - ncbi.nlm.nih.gov
Extracellular superoxide dismutase (EC-SOD) overexpression modulates cellular responses
such as tumor cell suppression and is induced by IFNγ. Therefore, we examined the role of …
such as tumor cell suppression and is induced by IFNγ. Therefore, we examined the role of …
[HTML][HTML] Deregulation of catalase, not MnSOD, is associated with necrotic death of p53-defective DF-1 cells under antimycin A-induced oxidative stress
S You, BW Kong, SY Jeon, DN Foster, H Kim - Molecules and cells, 2004 - Elsevier
One of distinct genetic alterations in spontaneously immortalized DF-1 cells was found to be
dysfunction of p53 and E2F-1 as well as altered antioxidant gene expression (upregulation …
dysfunction of p53 and E2F-1 as well as altered antioxidant gene expression (upregulation …
Molecular cloning and functional characterization of a cell-permeable superoxide dismutase targeted to lung adenocarcinoma cells: inhibition cell proliferation through …
M Lu, X Gong, Y Lu, J Guo, C Wang, Y Pan - Journal of Biological …, 2006 - ASBMB
In clinical oncology, many trials with superoxide dismutase (SOD) have failed to
demonstrate antitumor ability and in many cases even caused deleterious effects because of …
demonstrate antitumor ability and in many cases even caused deleterious effects because of …
Extracellular Superoxide Dismutase Induces Mouse Embryonic Fibroblast Proliferative Burst, Growth Arrest, Immortalization, and Consequent In Vivo Tumorigenesis
MD Castellone, A Langella, S Cantara… - Antioxidants & redox …, 2014 - liebertpub.com
Aims: Rat sarcoma virus (RAS)-induced tumorigenesis has been suggested to follow a three-
stage model consisting of an initial RAS activation, senescence induction, and evasion of …
stage model consisting of an initial RAS activation, senescence induction, and evasion of …
[HTML][HTML] Superoxide dismutase promotes the epithelial-mesenchymal transition of pancreatic cancer cells via activation of the H2O2/ERK/NF-κB axis
W Li, L Cao, L Han, Q Xu, Q Ma - … Journal of Oncology, 2015 - spandidos-publications.com
Our previous study revealed that superoxide dismutase (SOD)-dependent production of
reactive oxygen species (ROS) was able to increase the invasive ability of pancreatic cancer …
reactive oxygen species (ROS) was able to increase the invasive ability of pancreatic cancer …
Late ROS accumulation and radiosensitivity in SOD1-overexpressing human glioma cells
This study investigates the hypothesis that CuZn superoxide dismutase (SOD1)
overexpression confers radioresistance to human glioma cells by regulating the late …
overexpression confers radioresistance to human glioma cells by regulating the late …
Diallyl trisulfide-induced G2–M phase cell cycle arrest in human prostate cancer cells is caused by reactive oxygen species-dependent destruction and …
D Xiao, A Herman-Antosiewicz, J Antosiewicz, H Xiao… - Oncogene, 2005 - nature.com
Molecular mechanism of cell cycle arrest caused by diallyl trisulfide (DATS), a garlic-derived
cancer chemopreventive agent, has been investigated using PC-3 and DU145 human …
cancer chemopreventive agent, has been investigated using PC-3 and DU145 human …
Effects of manganese superoxide dismutase (MnSOD) expression on regulation of esophageal cancer cell growth and apoptosis in vitro and in nude mice
G Sun, Y Wang, W Hu, C Li - Tumor Biology, 2013 - Springer
Manganese superoxide dismutase (MnSOD) catalyzes superoxide radical (O 2−) into
hydrogen peroxide (H 2 O 2), which is further catalyzed by the combined action of …
hydrogen peroxide (H 2 O 2), which is further catalyzed by the combined action of …
Secretion of extracellular superoxide dismutase from muscle transduced with recombinant adenovirus inhibits the growth of B16 melanomas in mice
MD Wheeler, OM Smutney, RJ Samulski - Molecular Cancer Research, 2003 - AACR
A number of reports have described the effects of oxidative stress on tumor growth.
Therefore, these experiments were designed to test the hypothesis that overexpression of …
Therefore, these experiments were designed to test the hypothesis that overexpression of …