Advancements in nanotherapeutics for Alzheimer's disease: current perspectives

S Harilal, J Jose, DGT Parambi, R Kumar… - Journal of Pharmacy …, 2019 - academic.oup.com
Objectives Considerable progress has been made in the treatment of Alzheimer's disease
(AD), but all available strategies focus on alleviating symptoms rather than curing, which …

Nano-interventions for neurodegenerative disorders

C Fernandes, U Soni, V Patravale - Pharmacological research, 2010 - Elsevier
With an increase in lifespan and changing population demographics, the incidence of
central nervous system (CNS) diseases is expected to increase significantly in the 21st …

[HTML][HTML] Exploring the role of nanomedicines for the therapeutic approach of central nervous system dysfunction: at a glance

MM Rhaman, MR Islam, S Akash, M Mim… - Frontiers in Cell and …, 2022 - frontiersin.org
In recent decades, research scientists, molecular biologists, and pharmacologists have
placed a strong emphasis on cutting-edge nanostructured materials technologies to …

Nanoparticle technology and stem cell therapy team up against neurodegenerative disorders

C Vissers, G Ming, H Song - Advanced drug delivery reviews, 2019 - Elsevier
The convergence of nanoparticles and stem cell therapy holds great promise for the study,
diagnosis, and treatment of neurodegenerative disorders. Researchers aim to harness the …

Treatment of neurodegenerative disorders through the blood–brain barrier using nanocarriers

N Poovaiah, Z Davoudi, H Peng, B Schlichtmann… - Nanoscale, 2018 - pubs.rsc.org
Neurodegenerative diseases refer to disorders of the central nervous system (CNS) that are
caused by neuronal degradations, dysfunctions, or death. Alzheimer's disease, Parkinson's …

Physiological and pathological factors affecting drug delivery to the brain by nanoparticles

Y Islam, AG Leach, J Smith, S Pluchino… - Advanced …, 2021 - Wiley Online Library
The prevalence of neurological/neurodegenerative diseases, such as Alzheimer's disease is
known to be increasing due to an aging population and is anticipated to further grow in the …

Challenges and opportunities in CNS delivery of therapeutics for neurodegenerative diseases

TM Barchet, MM Amiji - Expert opinion on drug delivery, 2009 - Taylor & Francis
With an increase in lifespan and changing population demographics, the incidence of
central nervous system (CNS) diseases is expected to increase significantly in the 21st …

Theranostic applications of nanoparticles in neurodegenerative disorders

S Ramanathan, G Archunan, M Sivakumar… - International journal …, 2018 - Taylor & Francis
The preeminent treatments for neurodegenerative disease are often unavailable due to the
poor accessibility of therapeutic drugs. Moreover, the blood–brain barrier (BBB) effectively …

Nanotechnology-based drug delivery systems for targeting, imaging and diagnosis of neurodegenerative diseases

S Bozdağ Pehlivan - Pharmaceutical research, 2013 - Springer
Neurodegenerative disorders are becoming prevalent with the increasing age of the general
population. A number of difficulties have emerged for the potential treatment of …

[HTML][HTML] Nanocarriers as a powerful vehicle to overcome blood-brain barrier in treating neurodegenerative diseases: Focus on recent advances

X Niu, J Chen, J Gao - Asian journal of pharmaceutical sciences, 2019 - Elsevier
Neurodegenerative diseases including Alzheimer's disease, Parkinson's disease,
Huntington disease and amyotrophic lateral sclerosis throw a heavy burden on families and …