Alzheimer's disease (AD) is a neurodegenerative disorder that has become a compelling
global public health concern. Besides pathological hallmarks such as extracellular amyloid …

Neuronal network dysfunction is increasingly recognized as an early symptom in
Alzheimer's disease (AD) and may provide new entry points for diagnosis and intervention …

Interneurons, key regulators of hippocampal neuronal network excitability and
synchronization, are lost in advanced stages of Alzheimer's disease (AD). Given that …

In Alzheimer's disease (AD), a decline in explicit memory is one of the earliest signs of
disease and is associated with hippocampal dysfunction. Amyloid protein exerts a disruptive …

To understand the pathogenesis of specific neuronal circuit dysfunction in Alzheimer's
disease (AD), we investigated the fate of three subclasses of “modulatory interneurons” in …

Persistent activity in excitatory pyramidal cells is a putative mechanism for maintaining
memory traces during working memory. We recently demonstrated persistent interruption of …

Alzheimer's disease (AD) is characterized by progressive memory loss and cognitive
decline. These impairments correlate with early alterations in neuronal network activity in AD …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive
decline and amyloid-beta (Aβ) depositions generated by the proteolysis of amyloid …

Fast-spiking parvalbumin (PV) interneurons are inhibitory interneurons with unique
morphological and functional properties that allow them to precisely control local circuitry …

Alzheimer's disease (AD) is characterized by synaptic loss and neuronal network
dysfunction. These network deficits are mediated by early alterations in neuronal firing rates …