Low-cost frequency-domain photon migration instrument for tissue spectroscopy, oximetry, and imaging

Y Yang, H Liu, X Li, B Chance - Optical Engineering, 1997 - spiedigitallibrary.org
We described a low-cost, frequency-domain photon migration spectroscopy instrument by
using in-phase and quadrature demodulation technique in a 140-MHz homodyne system. A …

Portable, high-bandwidth frequency-domain photon migration instrument for tissue spectroscopy

SJ Madsen, ER Anderson, RC Haskell, BJ Tromberg - Optics letters, 1994 - opg.optica.org
We describe a novel frequency-domain photon migration instrument employing direct diode
laser modulation and avalanche photodiode detection, which is capable of noninvasively …

Frequency-domain photon migration measurements of normal and malignant tissue optical properties in a human subject

JB Fishkin, O Coquoz, ER Anderson, M Brenner… - Applied …, 1997 - opg.optica.org
A 1-GHz multifrequency, multiwavelength frequency-domain photon migration instrument is
used to measure quantitatively the optical absorption (μ_a) and effective optical scattering …

Multipixel techniques for frequency‐domain photon migration imaging

JS Reynolds, TL Troy… - Biotechnology …, 1997 - Wiley Online Library
The ability to map interior optical properties of a highly scattering medium from exterior
measurements of light propagation is afforded by optical tomography. In this communication …

Time-dependent optical spectroscopy and imaging for biomedical applications

BC Wilson, EM Sevick, MS Patterson… - Proceedings of the …, 1992 - ieeexplore.ieee.org
The application of optical spectroscopy and imaging in living tissue is complicated by
multiple scattering of light. In spectroscopy, this scattering causes uncertainty in the …

Time-resolved spectroscopy and imaging

B Chance - … , Photon Migration, and Spectroscopy of Tissue …, 1995 - spiedigitallibrary.org
In response to the conference organizer's request, I am presenting a summary of the current
status of medical optical imaging and spectroscopy. This is a topic which is advancing …

Development of time-resolved spectroscopy system for quantitative noninvasive tissue measurement

M Miwa, Y Ueda, B Chance - Optical Tomography, Photon …, 1995 - spiedigitallibrary.org
Near IR time resolved spectroscopy has been studied for quantitative determination of
absorbance in highly scattering medium such as tissue. When a very narrow optical pulse is …

Experimental study of migration depth for the photons measured at sample surface

W Cui, C Kumar, B Chance - Time-Resolved Spectroscopy …, 1991 - spiedigitallibrary.org
Optical imaging of in vivo tissue and noninvasive optical assessment of deep tissue requires
knowledge concerning photon migration paths in the medium. We used intralipid emulsion …

Determination of optical properties in semi-infinite turbid media using imaging measurements of frequency-domain photon migration obtained with an intensified …

M Gurfinkel, T Pan… - Journal of biomedical …, 2004 - spiedigitallibrary.org
Frequency-domain photon migration measurements across the surface of a tissue-
mimicking, semi-infinite phantom are acquired via an intensified charge-coupled device …

Frequency-domain measurements of photon migration in tissues

JR Lakowicz, K Berndt - Chemical physics letters, 1990 - Elsevier
We report the use of frequency-domain (FD) measurements to characterize time-dependent
migration of 620-740 nm photons in tissues, in particular arm and finger. The time …