Release of calcitonin gene-related peptide from dorsal root ganglion somata shapes neuronal excitability (autocrine) and glial activation (paracrine) in vitro

KL Knopp - 2007 - search.proquest.com
The somata of dorsal root ganglion neurons have historically been considered metabolic
depots that support the conducting axons with no other specific signaling function. Using …

Localization of functional calcitonin gene-related peptide binding sites in a subpopulation of cultured dorsal root ganglion neurons

GS von Banchet, A Pastor, C Biskup, C Schlegel… - Neuroscience, 2002 - Elsevier
In this study we investigated whether cultured dorsal root ganglion (DRG) neurons from the
adult rat express binding sites for calcitonin gene-related peptide (CGRP). These were …

Bradykinin and prostaglandin E1 regulate calcitonin gene-related peptide expression in cultured rat sensory neurons

SC Supowit, H Zhao, KA Katki, P Gupta, DJ DiPette - Regulatory peptides, 2011 - Elsevier
Primary cultures of adult rat dorsal root ganglia (DRG) sensory neurons were used to
determine whether bradykinin and prostaglandins E1 (PGE1), E2 (PGE2) or I2 (PGI2) …

Dexamethasone and activators of the protein kinase A and C signal transduction pathways regulate neuronal calcitonin gene-related peptide expression and release

SC Supowit, MD Christensen, KN Westlund… - Brain research, 1995 - Elsevier
Primary cultures of adult rat dorsal root ganglia (DRG) neurons were used to determine if
activation of either the protein kinase A or C signal transduction pathways or treatment with …

Calcitonin gene-related peptide immunoreactivity in neuronal perikarya in dorsal root

S Jeftinija, K Jeftinija - Brain Research, 1990 - Elsevier
Calcitonin gene-related peptide (CGRP) has been localized in neuronal cell bodies in
dorsal root ganglia (DRG) and in fibers of the dorsal horn (DH), where it may be involved in …

Cooperative regulation of calcitonin gene-related peptide levels in rat sensory neurons via their central and peripheral processes

Y Inaishi, Y Kashihara, M Sakaguchi… - Journal of …, 1992 - Soc Neuroscience
Calcitonin gene-related peptide (CGRP) is present in both motor and sensory neurons and
transported in the somatofugal direction. CGRP levels in sensory neurons are assumed to …

Ultrastructural studies on calcitonin gene-related peptide-, tachykinins-and somatostatin-immunoreactive neurones in rat dorsal root ganglia: evidence for the …

A Merighi, JM Polak, SJ Gibson, S Gulbenkian… - Cell and tissue …, 1988 - Springer
Calcitonin gene-related peptide (CGRP)-, tachykinins-and somatostatin-immunoreactive
neurones in rat dorsal root ganglia have been studied by means of single and double …

Calcitonin gene-related peptide release from intact isolated dorsal root and trigeminal ganglia

M Eberhardt, T Hoffmann, SK Sauer, K Messlinger… - Neuropeptides, 2008 - Elsevier
Neuropeptides like calcitonin gene-related peptide (CGRP) and substance P are found in
significant proportions of primary afferent neurons. Release of these neuropeptides as well …

Actions of calcitonin gene-related peptide on rat spinal dorsal horn neurons

PD Ryu, G Gerber, K Murase, M Randic - Brain research, 1988 - Elsevier
The membrane actions of calcitonin gene-related peptide (CGRP) and the effect on the Ca-
dependent action potential of dorsal horn neurons have been investigated by means of an …

Depolarization stimulates initial calcitonin gene-related peptide expression by embryonic sensory neurons in vitro

X Ai, SE MacPhedran, AK Hall - Journal of Neuroscience, 1998 - Soc Neuroscience
The neuropeptide calcitonin gene-related peptide (CGRP) is expressed by one-third of adult
rat lumbar dorsal root ganglion (DRG) neurons, many of which mediate pain sensation or …