Brain regions associated with the reversal of cocaine conditioned place preference by environmental enrichment
In addition to the known preventive effects of environmental enrichment (EE) on drug
addiction, we have recently shown that EE can also have “curative” effects and eliminate …
addiction, we have recently shown that EE can also have “curative” effects and eliminate …
Environmental enrichment reduces cocaine seeking and reinstatement induced by cues and stress but not by cocaine
C Chauvet, V Lardeux, SR Goldberg, M Jaber… - …, 2009 - nature.com
Whereas earlier studies have focused on the preventive effects of enriched environments
(EE) in drug addiction, in a recent study we suggested that EE can also have …
(EE) in drug addiction, in a recent study we suggested that EE can also have …
Reversal of cocaine addiction by environmental enrichment
M Solinas, C Chauvet, N Thiriet… - Proceedings of the …, 2008 - National Acad Sciences
Environmental conditions can dramatically influence the behavioral and neurochemical
effects of drugs of abuse. For example, stress increases the reinforcing effects of drugs and …
effects of drugs of abuse. For example, stress increases the reinforcing effects of drugs and …
Region and context-specific intracellular responses associated with cocaine-induced conditioned place preference expression
SK Nygard, A Klambatsen, B Balouch… - Neuroscience, 2015 - Elsevier
The development and maintenance of cocaine addiction depend heavily on learned reward-
environment associations that can induce drug-seeking behavior and relapse …
environment associations that can induce drug-seeking behavior and relapse …
Generalization of effects of environmental enrichment on seeking for different classes of drugs of abuse
Background Addiction is a chronic disease characterized by persistent vulnerability to
relapse during abstinence. In animal models of addiction, accumulating evidence suggests …
relapse during abstinence. In animal models of addiction, accumulating evidence suggests …
Role of the prelimbic subregion of the medial prefrontal cortex in acquisition, extinction, and reinstatement of cocaine-conditioned place preference
AR Zavala, SM Weber, HJ Rice, AT Alleweireldt… - Brain research, 2003 - Elsevier
Previous research suggests that the prelimbic subregion of the medial prefrontal cortex
(mPFC) is necessary for acquisition of cocaine-conditioned place preference (CPP) …
(mPFC) is necessary for acquisition of cocaine-conditioned place preference (CPP) …
Anti-craving effects of environmental enrichment
KJ Thiel, F Sanabria, NS Pentkowski… - International Journal …, 2009 - academic.oup.com
We hypothesized that environmental enrichment in rats may reduce cocaine-seeking
behaviour elicited by cocaine-priming injections and by cocaine-associated cues. Rats …
behaviour elicited by cocaine-priming injections and by cocaine-associated cues. Rats …
Altered prelimbic cortex output during cue-elicited drug seeking
CA Miller, JF Marshall - Journal of Neuroscience, 2004 - Soc Neuroscience
Cocaine treatment paired with environmental cues establishes a conditioned place
preference (CPP) for that environment. After expression of this preference, rats show …
preference (CPP) for that environment. After expression of this preference, rats show …
Effects of environmental enrichment on the incubation of cocaine craving
Recent studies have demonstrated that exposure to environmental enrichment (EE) during
withdrawal periods reduces the risks of relapse to drug-seeking behavior. In this study, we …
withdrawal periods reduces the risks of relapse to drug-seeking behavior. In this study, we …
Individual differences in cocaine-induced conditioned place preference in male rats: Behavioral and transcriptomic evidence
LA Atehortua Martinez, E Curis… - Journal of …, 2022 - journals.sagepub.com
Background: Substance use disorder emerges in a small proportion of drug users and has
the characteristics of a chronic relapsing pathology. Aims: Our study aimed to demonstrate …
the characteristics of a chronic relapsing pathology. Aims: Our study aimed to demonstrate …