IRRADIATION of the thoracic region can induce pathologic changes in normal lung tissue.
Although this reaction to radiation has been known for over thirty years, clinical recognition …

PULMONARY changes following radiation therapy for carcinoma of the lung were
recognized as early as 1898 (2) and have been described frequently since then. Clinical …

The cellular effects of irradiating the lungs are related to the histologic and clinical sequelae.
The occurrence and severity of damage are semiquantitatively related to the volume of lung …

1. Five patients with radiation pneumonitis and fibrosis leading to severe pulmonary
insufficiency are presented. Correlated clinical, functional and pathologic findings indicated …

With refinements in radiotherapeutic techniques in recent years, the incidence of pulmonary
damage attributable to irradiation has decreased. A significant number of patients, however …

IT is well recognized that the margin between a dose of X-rays that is therapeutically
effective arid one that produces undesirable damage to adjacent healthy tissue is always …

Abnormal pulmonary changes following radiation therapy over the lungs have long been
recognized and frequently described. The object of this paper is not a description of these …

The literature regarding pulmonary radiation damage is briefly reviewed and the clinical and
radiological pattern of the condition is described. 2. Four cases are recorded in which …

The degenerative and fibrotic changes produced by irradiation in all tissues are of especial
significance when their presence interferes with vital functions. One of those in which this …

After irradiation of the chest, usually for the treatment of metastatic disease, some patients
develop radiation pneumonitis which is characterized by an early stage and a late stage …