[HTML][HTML] Murine models of atrophy, cachexia, and sarcopenia in skeletal muscle
M Romanick, LDV Thompson… - Biochimica et Biophysica …, 2013 - Elsevier
With the extension of life span over the past several decades, the age-related loss of muscle
mass and strength that characterizes sarcopenia is becoming more evident and thus, has a …
mass and strength that characterizes sarcopenia is becoming more evident and thus, has a …
[HTML][HTML] Sarcopenia and muscle aging: a brief overview
The world is facing the new challenges of an aging population, and understanding the
process of aging has therefore become one of the most important global concerns …
process of aging has therefore become one of the most important global concerns …
Models of accelerated sarcopenia: critical pieces for solving the puzzle of age-related muscle atrophy
Sarcopenia, the age-related loss of skeletal muscle mass, is a significant public health
concern that continues to grow in relevance as the population ages. Certain conditions have …
concern that continues to grow in relevance as the population ages. Certain conditions have …
Experimental models of sarcopenia: bridging molecular mechanism and therapeutic strategy
S Mankhong, S Kim, S Moon, HB Kwak, DH Park… - Cells, 2020 - mdpi.com
Sarcopenia has been defined as a progressive decline of skeletal muscle mass, strength,
and functions in elderly people. It is accompanied by physical frailty, functional disability …
and functions in elderly people. It is accompanied by physical frailty, functional disability …
Age-related dysfunction in proteostasis and cellular quality control in the development of sarcopenia
Sarcopenia is a debilitating skeletal muscle disease that accelerates in the last decades of
life and is characterized by marked deficits in muscle strength, mass, quality, and metabolic …
life and is characterized by marked deficits in muscle strength, mass, quality, and metabolic …
Molecular and phenotypic analysis of rodent models reveals conserved and species-specific modulators of human sarcopenia
Sarcopenia, the age-related loss of skeletal muscle mass and function, affects 5–13% of
individuals aged over 60 years. While rodents are widely-used model organisms, which …
individuals aged over 60 years. While rodents are widely-used model organisms, which …
Animal models of sarcopenia
CJ Christian, GM Benian - Aging Cell, 2020 - Wiley Online Library
Sarcopenia is the age‐related decline in muscle mass and function without any underlying
disease. The exact molecular mechanisms responsible for this pathology remain unknown …
disease. The exact molecular mechanisms responsible for this pathology remain unknown …
[HTML][HTML] Molecular mechanisms and therapeutic interventions in sarcopenia
SS Park, ES Kwon, KS Kwon - Osteoporosis and sarcopenia, 2017 - Elsevier
Sarcopenia is the degenerative loss of muscle mass and function with aging. Recently
sarcopenia was recognized as a clinical disease by the International Classification of …
sarcopenia was recognized as a clinical disease by the International Classification of …
Mouse models of sarcopenia: classification and evaluation
W Xie, M He, D Yu, Y Wu, X Wang, S Lv… - Journal of cachexia …, 2021 - Wiley Online Library
Sarcopenia is a progressive and widespread skeletal muscle disease that is related to an
increased possibility of adverse consequences such as falls, fractures, physical disabilities …
increased possibility of adverse consequences such as falls, fractures, physical disabilities …
Role and potential mechanisms of anabolic resistance in sarcopenia
PH Haran, DA Rivas, RA Fielding - Journal of cachexia, sarcopenia and …, 2012 - Springer
There is pressing need to understand the aging process to better cope with its associated
physical and societal costs. The age-related muscle wasting known as sarcopenia is a major …
physical and societal costs. The age-related muscle wasting known as sarcopenia is a major …