Afferent lymphatic transport and peripheral tissue immunity

MM Steele, AW Lund - The Journal of Immunology, 2021 - journals.aai.org
Lymphatic vessels provide an anatomical framework for immune surveillance and adaptive
immune responses. Although appreciated as the route for Ag and dendritic cell transport …

Implications of lymphatic transport to lymph nodes in immunity and immunotherapy

SN Thomas, NA Rohner… - Annual review of …, 2016 - annualreviews.org
Adaptive immune response consists of many highly regulated, multistep cascades that
protect against infection while preserving the health of autologous tissue. The proper …

Structure and immune function of afferent lymphatics and their mechanistic contribution to dendritic cell and T cell trafficking

J Arasa, V Collado-Diaz, C Halin - Cells, 2021 - mdpi.com
Afferent lymphatic vessels (LVs) mediate the transport of antigen and leukocytes to draining
lymph nodes (dLNs), thereby serving as immunologic communication highways between …

[HTML][HTML] Lymphatic regulation of cellular trafficking

DG Jackson - Journal of clinical & cellular immunology, 2014 - ncbi.nlm.nih.gov
Lymphatic vessels play vital roles in immune surveillance and immune regulation by
conveying antigen loaded dendritic cells, memory T cells, macrophages and neutrophils …

Leucocyte trafficking via the lymphatic vasculature—mechanisms and consequences

DG Jackson - Frontiers in immunology, 2019 - frontiersin.org
The lymphatics fulfill a vital physiological function as the conduits through which leucocytes
traffic between the tissues and draining lymph nodes for the initiation and modulation of …

Lymphatic migration of immune cells

HR Hampton, T Chtanova - Frontiers in immunology, 2019 - frontiersin.org
Lymphatic vessels collect interstitial fluid that has extravasated from blood vessels and
return it to the circulatory system. Another important function of the lymphatic network is to …

The biophysics of lymphatic transport: engineering tools and immunological consequences

MJ O'Melia, AW Lund, SN Thomas - Iscience, 2019 - cell.com
Lymphatic vessels mediate fluid flows that affect antigen distribution and delivery, lymph
node stromal remodeling, and cell-cell interactions, to thus regulate immune activation. Here …

Immune traffic: a functional overview

A Beilhack, SG Rockson - Lymphatic research and biology, 2003 - liebertpub.com
The efficient function of the immune system necessitates the complex interaction of antigens,
antigen-presenting cells, and cell populations that modulate, regulate and effectuate the …

Pathogenic exploitation of lymphatic vessels

AI Magold, MA Swartz - Cells, 2022 - mdpi.com
Lymphatic vessels provide a critical line of communication between peripheral tissues and
their draining lymph nodes, which is necessary for robust immune responses against …

Initial afferent lymphatic vessels controlling outbound leukocyte traffic from skin to lymph nodes

A Teijeira, A Rouzaut, I Melero - Frontiers in immunology, 2013 - frontiersin.org
Tissue drains fluid and macromolecules through lymphatic vessels (LVs), which are lined by
a specialized endothelium that expresses peculiar differentiation proteins, not found in blood …