Background Inflammatory bowel disease (IBD) is considered a heterogeneous, complex
polygenic disease where both genetic and environmental factors are involved in the …

Inflammatory bowel diseases (IBD) are multifactorial disorders characterised by the host's
inability to limit the inflammatory response to luminal antigens. The association of …

The two major types of IBD are ulcerative colitis (UC) and Crohn's disease (CD), whose
etiology involves immunological and environmental factors. CD and UC share some …

Abstract Background and Aim Recent genomic studies have identified genetic variants in the
I L12B gene, which encodes the p40 subunit shared by interleukin 12 and interleukin 23, as …

AIM: To investigate the interaction of interleukin-23 receptor (IL23R)(rs1004819 and
rs2201841), autophagy-related 16-like 1 (ATG16L1)(rs2241880), caspase recruitment …

Dear Editors: Interleukin 6 (IL-6) is an important inflammatory cytokine. 1 It is reported that IL-
6 receptor (IL-6R) signaling is involved in the development of inflammatory bowel diseases …

Background. The etiology of inflammatory bowel disease, which includes ulcerative colitis
and Crohn's disease, has not yet been made clear. However, inflammatory bowel disease is …

Epidemiological and genome-wide linkage analyses have provided firm evidence for a
genetic component in the pathogenesis of inflammatory bowel disease. The linkage regions …

Inflammatory bowel diseases (IBD) and colorectal cancer (CRC) are disorders that originate
from immune disturbances. In our study, we evaluated the association between the− 251 T/A …

Objective. There is strong evidence that genetic factors contribute to the susceptibility for
inflammatory bowel diseases (IBD). Recently, IL-18 promoter polymorphisms were …