Weight loss and cardiovascular disease risk outcomes of semaglutide: a one-year multicentered study

W Ghusn, S Fansa, D Anazco, E Tama… - International Journal of …, 2024 - nature.com
Abstract Background/Objective There are limited real-world studies assessing semaglutide
weight loss and associated comorbidity and metabolic outcomes over periods≥ 6 months …

Semaglutide improves cardiometabolic risk factors in adults with overweight or obesity: STEP 1 and 4 exploratory analyses

MN Kosiborod, M Bhatta, M Davies… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aims Evaluate the effects of once‐weekly subcutaneous semaglutide 2.4 mg on
cardiometabolic risk factors in people with overweight/obesity without diabetes in the STEP …

Two-year effect of semaglutide 2.4 mg vs placebo in adults with overweight or obesity: STEP 5

M Bhatta, S Buscemi, J Frias, GMF Rigas - Obesity, 2021 - search.proquest.com
Background: The 2-year efficacy and safety of once-weekly (OW) subcutaneous semaglutide
2.4 mg vs placebo in adults with overweight/obesity was assessed in the STEP 5 phase 3 …

Semaglutide 2.4 mg clinical outcomes in patients with obesity or overweight in a real‐world setting: A 6‐month retrospective study in the United States (SCOPE)

A Ruseva, W Michalak, Z Zhao… - Obesity Science & …, 2024 - Wiley Online Library
Background Management guidelines for obesity suggest maintaining a minimum of 5% body
weight reduction to help prevent or lower the risk of developing conditions such as …

Impact of BMI and comorbidities on efficacy of once‐weekly semaglutide: Post hoc analyses of the STEP 1 randomized trial

BM McGowan, A Houshmand‐Oeregaard… - …, 2023 - Wiley Online Library
Objective This study assessed the effects of semaglutide on body weight, cardiometabolic
risk factors, and glycemic status in individuals categorized by baseline BMI with or without …

Once-weekly semaglutide in adults with overweight or obesity

JPH Wilding, RL Batterham, S Calanna… - … England Journal of …, 2021 - Mass Medical Soc
Background Obesity is a global health challenge with few pharmacologic options. Whether
adults with obesity can achieve weight loss with once-weekly semaglutide at a dose of 2.4 …

Semaglutide for weight loss and cardiometabolic risk reduction in overweight/obesity

AC Mares, S Chatterjee… - Current Opinion in …, 2022 - journals.lww.com
Semaglutide for weight loss and cardiometabolic risk reducti... : Current Opinion in Cardiology
Semaglutide for weight loss and cardiometabolic risk reduction in overweight/obesity : Current …

Semaglutide for the treatment of overweight and obesity: a review

NC Bergmann, MJ Davies, I Lingvay… - Diabetes, Obesity and …, 2023 - Wiley Online Library
Obesity is a chronic, relapsing disease associated with multiple complications and a
substantial morbidity, mortality and health care burden. Pharmacological treatments for …

Weight loss outcomes associated with semaglutide treatment for patients with overweight or obesity

W Ghusn, A De la Rosa, D Sacoto… - JAMA Network …, 2022 - jamanetwork.com
Importance No retrospective cohort study has assessed the effectiveness of semaglutide at
doses used in randomized clinical trials to treat obesity (ie, 1.7 and 2.4 mg). Objective To …

Efficacy and safety of once-weekly semaglutide in adults with overweight or obesity: a meta-analysis

P Zhong, H Zeng, M Huang, W Fu, Z Chen - Endocrine, 2022 - Springer
Purpose This meta-analysis aimed to assess the efficacy and safety of once-weekly
semaglutide among adults with overweight or obesity. Methods We searched multiple …