Towards the human colorectal cancer microbiome

JR Marchesi, BE Dutilh, N Hall, WHM Peters… - PloS one, 2011 - journals.plos.org
Multiple factors drive the progression from healthy mucosa towards sporadic colorectal
carcinomas and accumulating evidence associates intestinal bacteria with disease initiation …

Microbiome in colorectal cancer: how to get from meta-omics to mechanism?

D Ternes, J Karta, M Tsenkova, P Wilmes, S Haan… - Trends in …, 2020 - cell.com
Mounting evidence from metagenomic analyses suggests that a state of pathological
microbial imbalance or dysbiosis is prevalent in the gut of patients with colorectal cancer …

The intestinal microbiota in colorectal cancer

H Tilg, TE Adolph, RR Gerner, AR Moschen - Cancer cell, 2018 - cell.com
Experimental evidence from the past years highlights a key role for the intestinal microbiota
in inflammatory and malignant gastrointestinal diseases. Diet exhibits a strong impact on …

The microbial landscape of colorectal cancer

MT White, CL Sears - Nature Reviews Microbiology, 2024 - nature.com
Colorectal cancer (CRC) is a substantial source of global morbidity and mortality in dire
need of improved prevention and treatment strategies. As our understanding of CRC grows …

Mucosal adherent bacterial dysbiosis in patients with colorectal adenomas

Y Lu, J Chen, J Zheng, G Hu, J Wang, C Huang… - Scientific reports, 2016 - nature.com
Recent reports have suggested that the gut microbiota is involved in the progression of
colorectal cancer (CRC). The composition of gut microbiota in CRC precursors has not been …

[HTML][HTML] Microbiome and colorectal cancer: Roles in carcinogenesis and clinical potential

E Saus, S Iraola-Guzmán, JR Willis… - Molecular aspects of …, 2019 - Elsevier
The gastrointestinal tract harbors most of the microbiota associated with humans. In recent
years, there has been a surge of interest in assessing the relationships between the gut …

Colorectal cancer-associated microbiome patterns and signatures

L Zhao, WC Cho, MR Nicolls - Frontiers in Genetics, 2021 - frontiersin.org
The gut microbiome is dynamic and shaped by diet, age, geography, and environment. The
disruption of normal gut microbiota (dysbiosis) is closely related to colorectal cancer (CRC) …

Gut microbiota dysbiosis drives the development of colorectal cancer

X Fan, Y Jin, G Chen, X Ma, L Zhang - Digestion, 2021 - karger.com
Background: The gut microbiota is a diverse community of microbes that maintain the
stability of the intestinal environment. Dysbiosis of the gut microbiota has been linked to …

Dysbiosis of gut microbiota in promoting the development of colorectal cancer

S Zou, L Fang, MH Lee - Gastroenterology report, 2018 - academic.oup.com
Gastrointestinal microbiome, containing at least 100 trillion bacteria, resides in the mucosal
surface of human intestine. Recent studies show that perturbations in the microbiota may …

Significance of the gut microbiome in multistep colorectal carcinogenesis

S Mizutani, T Yamada, S Yachida - Cancer Science, 2020 - Wiley Online Library
Colorectal cancer (CRC) is highly prevalent worldwide. In 2018, there were over 1.8 million
new cases. Most sporadic CRC develop from polypoid adenomas and are preceded by …