New horizons in the treatment of osteosarcoma

PS Meltzer, LJ Helman - New England Journal of Medicine, 2021 - Mass Medical Soc
Osteosarcoma Osteosarcoma, which is most common in people 10 to 30 years of age, is
generally treated with resection and adjuvant chemotherapy. Detection of gene …

[HTML][HTML] Osteosarcoma: accelerating progress makes for a hopeful future

AJ Saraf, JM Fenger, RD Roberts - Frontiers in oncology, 2018 - frontiersin.org
Patients who develop osteosarcoma in 2017 receive treatment that remains essentially
unchanged since the 1970s. Outcomes likewise remain largely unimproved. Large …

[HTML][HTML] Osteosarcoma: current treatment and a collaborative pathway to success

MS Isakoff, SS Bielack, P Meltzer… - Journal of clinical …, 2015 - ncbi.nlm.nih.gov
Osteosarcoma is the bone tumor that most commonly affects children, adolescents, and
young adults. Before 1970, treatment primarily included surgical resection. However, the …

[PDF][PDF] Osteosarcoma: a review of diagnosis, management, and treatment strategies

DS Geller, R Gorlick - Clin Adv Hematol Oncol, 2010 - hematologyandoncology.net
Despite significant advancements in the diagnosis and treatment of osteosarcoma to date,
overall survival has remained relatively constant for over 2 decades. The challenge in …

Advancing therapy for osteosarcoma

J Gill, R Gorlick - Nature reviews Clinical oncology, 2021 - nature.com
Improving the survival of patients with osteosarcoma has long proved challenging, although
the treatment of this disease is on the precipice of advancement. The increasing feasibility of …

Pathogenesis and current treatment of osteosarcoma: perspectives for future therapies

R Rathore, BA Van Tine - Journal of clinical medicine, 2021 - mdpi.com
Osteosarcoma is the most common primary malignant bone tumor in children and young
adults. The standard-of-care curative treatment for osteosarcoma utilizes doxorubicin …

Update on targets and novel treatment options for high-grade osteosarcoma and chondrosarcoma

JG van Oosterwijk, JK Anninga… - Hematology …, 2013 - hemonc.theclinics.com
Update on Targets and Novel Treatment Options for High-Grade Osteosarcoma and
Chondrosarcoma - Hematology/Oncology Clinics Skip to Main Content Advertisement …

New targets and approaches in osteosarcoma

J Gill, MK Ahluwalia, D Geller, R Gorlick - Pharmacology & therapeutics, 2013 - Elsevier
Osteosarcoma is the most common primary tumor of bone. Approximately 2/3 of patients
who present with localized osteosarcoma can be expected to be cured of their disease with …

The current and future therapies for human osteosarcoma

JD Lamplot, S Denduluri, J Qin, R Li… - Current cancer …, 2013 - ingentaconnect.com
Osteosarcoma (OS) is the most common non-hematologic malignant tumor of bone in adults
and children. As sarcomas are more common in adolescents and young adults than most …

Management of osteosarcoma

J Whelan, B Seddon, M Perisoglou - Current Treatment Options in …, 2006 - Springer
Opinion statement Improving cure rates for osteosarcoma continues to be a major challenge.
The clinical management of individual patients is exacting and requires a skilled …