Survival in osteosarcoma is a story of success on many fronts. What was once a disease that
was rarely curable even with ablative surgery now has a 5-year overall survival approaching …

The treatment of osteosarcoma requires a multidisciplinary approach involving the family
physician, orthopedic oncologist, medical oncologist, radiologist and pathologist …

Osteosarcoma (OS) is the most common type of primary solid tumor that develops in bone.
Although standard chemotherapy has significantly improved long‐term survival over the past …

Despite advances in diagnostic imaging, the evolution of neoadjuvant chemotherapy and
the refinements in limb-salvage surgery, the progression-free survival rate remains poor for …

Traditional prognostic determinants in osteosarcoma have included demographics (age,
sex), tumour size, site, stage, and the response to chemotherapy. Many of these are …

Abstract Learning Objectives After completing this course, the reader will be able to: Discuss
etiologic and biologic factors in osteosarcoma. Select the appropriate diagnostic work-up for …

Osteosarcoma is the most common primary malignant bone tumor in children and
adolescents. Despite significant clinical improvements over the past several decades …

Osteosarcoma (OS) is a primary malignant bone tumor that most commonly affects children,
adolescents, and young adults. Here, we comprehensively analyze genomic, epigenomic …

Osteosarcoma (OS) is the most common primary bone malignancy and is frequently lethal
via metastasis to the lung. While surgical techniques and adjuvant chemotherapies have …

Osteosarcoma is the predominant form of bone cancer, affecting mostly adolescents. Recent
progress made in molecular genetic studies of osteosarcoma has changed our view on the …