Airway epithelial barrier dysfunction is frequently observed in asthma and may have
important implications. The physical barrier function of the airway epithelium is tightly …

The integrity of the airway epithelium in patients with asthma is often disrupted, with loss of
epithelial cell–cell contacts. Airway epithelial barrier dysfunction may have important …

Asthma was previously defined as an allergic Th2‐mediated inflammatory immune disorder.
Recently, this paradigm has been challenged because not all pathological changes …

Asthma is a chronic inflammatory airway disease characterized by variable airflow
obstruction in response to a wide range of exogenous stimuli. The airway epithelium is the …

Asthma is a global health problem with increasing prevalence. The airway epithelium is the
initial barrier against inhaled noxious agents or aeroallergens. In asthma, the airway …

Asthma is a chronic inflammatory disease of the respiratory tract characterized by recurrent
breathing problems resulting from airway obstruction and hyperresponsiveness. Human …

The respiratory epithelium provides a physical, functional, and immunologic barrier to
protect the host from the potential harming effects of inhaled environmental particles and to …

Asthma is an inflammatory disorder principally involving the conducting airways and
characterised by infiltration of the airway wall with a range of inflammatory cells driven in …

Mucosal inflammation and more recently airway remodeling continue to be a focus of
interest when considering both the pathophysiology and treatment of asthma. Although a …

Asthma is an inflammatory disorder of the airways dominated by a Th2-type pattern.
Because of this, most research has focused on investigating the role of allergic pathways …