It is becoming increasingly clear that the airway epithelium orchestrates inflammatory and
remodeling responses of the airway. Understanding the regulatory mechanisms involved in …

Asthma is a common disorder of the airways characterized by airway inflammation and by
decline in lung function and airway remodeling in a subset of asthmatics. Airway remodeling …

Asthma is a disorder of the airways in which Th-2-mediated inflammation is considered to
provide the basis for altered structure and function that leads to bronchial hyper …

A substantial proportion of healthcare cost associated with asthma is attributable to
exacerbations of the disease. Within the airway, the epithelium forms the mucosal immune …

Asthma is described as a chronic inflammatory disorder of the conducting airways. It is
characterized by reversible airway obstruction, eosinophil and Th2 infiltration, airway hyper …

Asthma is a chronic inflammatory disease characterized by reversible airflow limitation and
airway hyperresponsiveness. Persistent inflammation in airway tissues may lead to …

Chronic exposure to environmental pollutants is a major contributor to the development and
progression of obstructive airway diseases, including asthma and COPD. Understanding the …

Asthma is one of the most common chronic diseases affecting both children and adults. We
report a genome-wide association meta-analysis of 69,189 cases and 702,199 controls from …

Background Asthma exacerbations are associated with heightened asthma symptoms,
which can result in hospitalization in severe cases. However, the molecular immunologic …

The airway epithelium protects us from environmental insults, which we encounter with
every breath. Not only does it passively filter large particles, it also senses potential danger …