Estrogen receptor quantitative measures and breast cancer survival

DA Hill, M Barry, C Wiggins, A Nibbe, M Royce… - Breast cancer research …, 2017 - Springer
Purpose While the estrogen receptor (ER) is the single most widely used biomarker to
evaluate breast cancer outcomes, aspects of ER marker biology remain poorly understood …

Quantitative measures of estrogen receptor expression in relation to breast cancer-specific mortality risk among white women and black women

H Ma, Y Lu, PA Marchbanks, SG Folger, BL Strom… - Breast Cancer …, 2013 - Springer
Introduction The association of breast cancer patients' mortality with estrogen receptor (ER)
status (ER+ versus ER-) has been well studied. However, little attention has been paid to the …

Only estrogen receptor “positive” is not enough to predict the prognosis of breast cancer

JM Ryu, HJ Choi, I Kim, SK Lee, J Yu, JE Kim… - Breast Cancer Research …, 2018 - Springer
Purpose Beginning in 2018, biomarkers including estrogen receptor (ER) status were
incorporated in the 8th AJCC staging system. ER expression levels were not considered in …

[HTML][HTML] Multimodal assessment of estrogen receptor mRNA profiles to quantify estrogen pathway activity in breast tumors

A Muthukaruppan, A Lasham, KJ Woad, MA Black… - Clinical Breast …, 2017 - Elsevier
Background Molecular markers have transformed our understanding of the heterogeneity of
breast cancer and have allowed the identification of genomic profiles of estrogen receptor …

Estrogen receptor breast cancer phenotypes in the Surveillance, Epidemiology, and End Results database

WF Anderson, N Chatterjee, WB Ershler… - Breast cancer research …, 2002 - Springer
Background. Researchers question whether estrogen receptorα-negative (ERN) and-
positive (ERP) represent different stages of one disease or different breast cancer types …

Prognostic significance of estrogen receptor status in breast cancer in relation to tumor stage, axillary node metastasis, and histopathologic grading

FF Parl, BP Schmidt, WD Dupont, RK Wagner - Cancer, 1984 - Wiley Online Library
The value of estrogen receptor (ER) measurements for predicting recurrence and survival
rates in primary breast cancer was examined in 121 women who were followed from 5 to 12 …

Estrogen receptor analysis for breast cancer: current issues and keys to increasing testing accuracy

LK Diaz, N Sneige - Advances in anatomic pathology, 2005 - journals.lww.com
The estrogen receptor (ER) is a regulator of cellular growth, proliferation, and differentiation.
In addition to having prognostic value, ER is the most important biologic marker of …

Estrogen receptor negative/progesterone receptor positive breast cancer is not a reproducible subtype

MM Hefti, R Hu, NW Knoblauch, LC Collins… - Breast Cancer …, 2013 - Springer
Introduction Estrogen receptor (ER) and progesterone receptor (PR) testing are performed in
the evaluation of breast cancer. While the clinical utility of ER as a predictive biomarker to …

Racial differences in estrogen receptor staining levels and implications for treatment and survival among estrogen receptor positive, HER2-negative invasive breast …

KS Purrington, D Gorski, MS Simon, TA Hastert… - Breast cancer research …, 2020 - Springer
Abstract Background African American women (AAW) die more frequently from estrogen
receptor (ER) positive breast cancer than European American women (EAW). We …

Estrogen receptor (ER) mRNA and ER-related gene expression in breast cancers that are 1% to 10% ER-positive by immunohistochemistry

T Iwamoto, D Booser, V Valero, JL Murray… - Journal of Clinical …, 2012 - ascopubs.org
Purpose We examined borderline estrogen receptor (ER)–positive cancers, defined as
having 1% to 10% positivity by immunohistochemistry (IHC), to determine whether they …