Objective. The main causes of death in severe pancreatitis are multiorgan failure and septic
complications. Prophylactic treatment with effective antibiotics is therefore a tempting …

Objective We compared two imipenem regimens for prevention of septic complications in
patients with severe acute necrotizing pancreatitis (ANP). Design and setting Prospective …

Objectives Prophylactic antibiotics are helpful in decreasing the incidence of septic
complications in acute pancreatitis. The aim of this study was to compare the efficacy of …

Background & Aims: Antibiotic prophylaxis in severe pancreatitis has recently yielded
promising clinical results, with imipenem significantly reducing the incidence of infected …

Acute pancreatitis is an inflammatory disorder, but it is not generally caused by infectious
agents. Yet, in tertiary referral hospitals, the majority of patients who die of necrotizing …

Bacterial infection of pancreatic necrotic tissue is a frequent complication of severe acute
pancreatitis. Infected pancreatic necrotic tissue is observed in 30–70% of all patients …

Pancreatic infection is the main indication for surgery and the principal determinant of
prognosis in acute necrotizing pancreatitis. Previous studies on the effects of antibiotics …

Background & Aims: Antibiotic prophylaxis in necrotizing pancreatitis remains controversial.
Until now, there have been no double-blind studies dealing with this topic. Methods: A total …

The most important risk factor in patients suffering from acute necrotizing pancreatitis is
pancreatic infection, a factor that determines the course of the disease, its therapeutic …

Death from acute severe pancreatitis results from infection and multiple organ system failure
occurring late in the course of illness. Patients with necrotizing pancreatitis involving at least …