Recurrent translocation t(10;17)(p15;q21) in minimally differentiated acute myeloid leukemia results in ZMYND11/MBTD1 fusion

JDE de Rooij… - Genes …, 2016 - Wiley Online Library
Pediatric acute myeloid leukemia (AML) is a heterogeneous disease, characterized by
different collaborating karyotypic and molecular abnormalities, which are used in risk group …

Recurrent translocation (10;17)(p15;q21) in acute poorly differentiated myeloid leukemia likely results in ZMYND11–MBTD1 fusion

E De Braekeleer, R Auffret, N Douet-Guilbert… - Leukemia & …, 2014 - Taylor & Francis
Translocation (10; 17)(p15; q21) is a recurrent abnormality that has been reported in only
seven cases of acute leukemia, including two by our group [1](available at: http://cgap. nci …

Expression of a novel ZMYND11/MBTD1 fusion transcript in CD7+CD56+ acute myeloid leukemia with t(10;17)(p15;q21)

K Yamamoto, K Yakushijin, H Ichikawa… - Leukemia & …, 2018 - Taylor & Francis
The t (10; 17)(p15; q21) translocation is a very rare but recurrent cytogenetic aberration in
acute myeloid leukemia (AML), which would be classified as AML, not otherwise specified …

[HTML][HTML] ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association …

J Li, PM Galbo Jr, W Gong, AJ Storey, YH Tsai… - Nature …, 2021 - nature.com
Abstract Recurring chromosomal translocation t (10; 17)(p15; q21) present in a subset of
human acute myeloid leukemia (AML) patients creates an aberrant fusion gene termed …

Banding and molecular cytogenetic studies detected a CBFB-MYH11 fusion gene that appeared as abnormal chromosomes 1 and 16 in a baby with acute myeloid …

MLM Silva, SC Raimondi, E Abdelhay, M Gross… - Cancer genetics and …, 2008 - Elsevier
The acute myeloid leukemia (AML) subtype M4Eo occurs in 5% of all AML cases and is
usually associated with either an inv (16)(p13. 1q22) or at (16; 16)(p13. 1; q22) …

[PDF][PDF] A novel specific signature of pediatric MOZ-CBP acute myeloid leukemia

S Serravalle, F Melchionda, A Astolfi, V Libri… - Leukemia …, 2010 - sfera.unife.it
The reciprocal chromosomal rearrangement t (8; 16)(p11; p13) is rare both in adult and
pediatric acute myeloid leukemias (AML) accounting 0.2–0.4% of de novo AML and 6.5% of …

Gene Expression Profiling of Acute Myeloid Leukemia with Translocation t(8;16)(p11;p13) and MYST3-CREBBP Rearrangement Reveals a Distinctive Signature with a Specific …

M Camós, J Esteve, P Jares, D Colomer, M Rozman… - Cancer research, 2006 - AACR
Acute myeloid leukemia (AML) with translocation t (8; 16)(p11; p13) is an infrequent
leukemia subtype with characteristic clinicobiological features. This translocation leads to …

Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors

JM Barajas, M Rasouli, M Umeda, R Hiltenbrand… - Blood, 2024 - ashpublications.org
UBTF tandem duplications (UBTF-TDs) have recently emerged as a recurrent alteration in
pediatric and adult acute myeloid leukemia (AML). UBTF-TD leukemias are characterized by …

Genome profiling of acute myelomonocytic leukemia: alteration of the MYB locus in MYST3-linked cases

A Murati, C Gervais, N Carbuccia, P Finetti, N Cervera… - Leukemia, 2009 - nature.com
Abstract The t (8; 16)(p11; p13) is a rare translocation involved in de novo and therapy-
related myelomonocytic and monocytic acute leukemia. It fuses two genes encoding histone …

RT-PCR and FISH analysis of acute myeloid leukemia with t (8; 16)(p11; p13) and chimeric MOZ and CBP transcripts: breakpoint cluster region and clinical …

HH Schmidt, S Strehl, D Thaler, D Strunk, H Sill… - Leukemia, 2004 - nature.com
Abstract The translocation t (8; 16)(p11; p13) is associated with acute myeloid leukemia
displaying monocytic differentiation (AML FAB M4/5) and fuses the MOZ (also named …