YES-associated protein 1 promotes adenocarcinoma growth and metastasis through activation of the receptor tyrosine kinase Axl

ZL Cui, FF Han, XH Peng, X Chen… - International journal …, 2012 - journals.sagepub.com
Yes-associated protein 1 (YAP1), a nuclear effector of the Hippo pathway, plays an
important role in tumorigenesis and progression of multiple cancers. The present study …

Overexpression of yes‐associated protein contributes to progression and poor prognosis of non‐small‐cell lung cancer

Y Wang, Q Dong, Q Zhang, Z Li, E Wang… - Cancer science, 2010 - Wiley Online Library
Yes‐associated protein (YAP), the nuclear effector of the Hippo pathway, is a key regulator
of organ size and a candidate human oncogene. This study aimed to assess the clinical …

Yes-associated protein 1 exhibits oncogenic property in gastric cancer and its nuclear accumulation associates with poor prognosis

W Kang, JHM Tong, AWH Chan, TL Lee… - Clinical Cancer …, 2011 - AACR
Abstract Purpose: Yes-associated protein 1 (YAP1) is a multifunctional protein that can
interact with different transcription factors to activate gene expression. The role of YAP1 in …

[HTML][HTML] Yes-associated protein enhances proliferation and attenuates sensitivity to cisplatin in human gastric cancer cells

T Lu, L Sun, X Zhu - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Background Yes-associated protein (YAP) is upregulated in many cancer types, and its
overexpression is involved in tumor cell proliferation, metastasis and resistance to …

[HTML][HTML] Yes-associated protein expression is correlated to the differentiation of prostate adenocarcinoma

MG Noh, SS Kim, EC Hwang… - Journal of pathology …, 2017 - synapse.koreamed.org
Background Yes-associated protein (YAP) in the Hippo signaling pathway is a growth
control pathway that regulates cell proliferation and stem cell functions. Abnormal regulation …

Expression and Yes-associated protein in gastric adenocarcinoma and inhibitory effects of its knockdown on gastric cancer cell proliferation and metastasis

J Zhang, ZP Xu, YC Yang, JS Zhu… - International journal …, 2012 - journals.sagepub.com
Yes-associated protein (YAP) has been implicated as an oncogene in multiple human
cancers. In the present study, human gastric adenocarcinoma tissues of different grades (N …

Nuclear expression of Yes-associated protein 1 correlates with poor prognosis in intestinal type gastric cancer

M Song, JH Cheong, H Kim, SH Noh… - Anticancer research, 2012 - ar.iiarjournals.org
Background: Yes-associated protein 1 (YAP1) is an effector of the Hippo pathway, which is
critical for regulating organ size and cell proliferation in mammals. To investigate the …

YAP1 is involved in tumorigenic properties of prostate cancer cells

FK Collak, U Demir, F Sagir - Pathology & Oncology Research, 2020 - Springer
Abstract The Yes Associated Protein 1 (YAP1) is a transcriptional cofactor negatively
regulated by Hippo Pathway. The dysregulation of the pathway has been shown to have a …

High nuclear expression of yes-associated protein 1 correlates with metastasis in patients with breast cancer

YJ Cha, SJ Bae, D Kim, SG Ahn, J Jeong… - Frontiers in …, 2021 - frontiersin.org
Background Yes-associated protein 1 (YAP1) is a transcription factor regulated by the Hippo
pathway and functions as an oncogene in various solid tumors under dysregulated Hippo …

Knockdown of YAP inhibits growth in Hep-2 laryngeal cancer cells via epithelial-mesenchymal transition and the Wnt/β-catenin pathway

X Tang, Y Sun, G Wan, J Sun, J Sun, C Pan - BMC cancer, 2019 - Springer
Background Yes-associated protein (YAP) plays a crucial role in tumour development and it
is the main effector of the Hippo signalling pathway. However, the mechanism underlying …