[PDF][PDF] PET in drug discovery and development: an introduction

H Scheinin, J Knuuti, M Scheinin - Annals of Medicine, 1999 - Taylor & Francis
The development of a new drug is an extremely expensive and risky venture. The average
cost per a successful new chemical entity is estimated to exceed USD 200 million, and after …

Introduction on pet: Description of basics and principles

A Waarde - Trends On The Role Of Pet In Drug Development, 2012 - World Scientific
Positron emission tomography (or PET) is a non-destructive imaging technique in nuclear
medicine with several unique properties: high sensitivity, low radiation dose, possibility to …

[图书][B] PET for drug development and evaluation

D Comar - 2012 - books.google.com
Can drug development and evaluation be improved by the use of positron emission
tomography (PET)? PET is now well established and many PET centres participate in …

New directions in positron emission tomography

JS Fowler, AP Wolf - Annual Reports in Medicinal Chemistry, 1989 - Elsevier
Publisher Summary This chapter describes the design and synthesis of radiotracers labeled
with the short lived cyclotron produced nuclides and the application of positron emission …

Multi-tracer syntheses at a radiopharmaceutical production centre'A shift of paradigm'

M Nader - 2007 - osti.gov
Full text: The positron emission tomography (PET) is an unique, non-invasive, powerful
diagnostic tool at the forefront of modern functional imaging in clinical nuclear medicine …

Positron emission tomography: radioisotope and radiopharmaceutical production.

HJ Tochon-Danguy, JI Sachinidis, GF Egan… - … Sciences in Medicine, 1999 - europepmc.org
A Centre for Positron Emission Tomography (PET) has been operational within the
Department of Nuclear Medicine at the Austin & Repatriation Medical Centre (A&RMC) in …

Positron emission tomography: applications in drug discovery and drug development

J Wang, L Maurer - Current topics in medicinal chemistry, 2005 - ingentaconnect.com
Positron Emission Tomography (PET) is a sophisticated nuclear imaging modality that
affords researchers the ability to conduct both functional and molecular imaging on …

[PDF][PDF] PET tracers and radiochemistry

DJ Schlyer - ANNALS-ACADEMY OF MEDICINE SINGAPORE, 2004 - annals.edu.sg
This paper provides a brief review of the radiochemistry of radiopharmaceuticals used in
positron emission tomography (PET). It includes some history of PET, the basic formation of …

Cyclotrons and Positron Emitting Radiopharmaceuticals

AP Wolf, JS Fowler - Physics and Engineering of Medical Imaging, 1987 - Springer
Abstract Positron Emission Tomography is at the present time in a growth phase with an
increasing number of clinical facilities showing interest in the use of PET in routine practice …

History of PET

ME Phelps - Practical FDG imaging: A teaching file, 2002 - Springer
There are three major technical components of positron emission tomography (PET): PET
scanner, cyclotron production of radiopharmaceuticals, and biological assays of normal and …