[引用][C] Positron instrumentation

GL Brownell, JA Correia… - Recent advances in …, 1978 - Grune & Stratton New York

Positron emission tomography

BS Koetz, P Price - Radiotracers in Drug Development, 2006 - taylorfrancis.com
Positron emission tomography (PET) has the potential for in vivo imaging of drug
pharmacokinetics, pharmacodynamic endpoints, molecular pathways, and gene expression …

[PDF][PDF] Positron emission tomography-illuminating in vivo drug disposition

P Hartvig, KJ Lindner, J Tedroff… - European Journal of …, 1994 - academia.edu
Positron emission tomography, PET, is a noninvasive tracer technique which quantitates the
kinetics of a radiotracer in a biochemical or physiological process in the tissue of the living …

Molecular PET instrumentation and imaging techniques

R Lecomte - Molecular imaging in oncology, 2008 - taylorfrancis.com
Positron emission tomography (PET) is a nuclear medicine imaging technique that provides
a powerful and sensitive means to noninvasively investigate biological processes in vivo …

Quantification in positron emission tomography for research in pharmacology and drug development

VJ Cunningham, RN Gunn… - Nuclear medicine …, 2004 - journals.lww.com
Positron emission tomography (PET) is a quantitative in vivo tracer technique, enabling
images of the distribution of biochemical, physiological and pharmacological functions in …

Principles and clinical applications of positron emission tomography

SF Gardner, JA Green, EM Bednarczyk… - American journal of …, 1992 - academic.oup.com
The basics of positron emission tomography (PET) are presented, including the physics,
instrumentation, and radiopharmaceuticals involved; the clinical and research applications; …

Positron-emitting isotopes produced on biomedical cyclotrons

P McQuade, DJ Rowland, JS Lewis… - Current medicinal …, 2005 - ingentaconnect.com
This review will discuss the production and applications of positron-emitting radionuclides
for use in Positron Emission Tomography (PET), with emphasis on radionuclides that can be …

Positron emission tomography microdosing: a new concept with application in tracer and early clinical drug development

M Bergström, A Grahnen, B Långström - European journal of clinical …, 2003 - Springer
The realisation that new chemical entities under development as drug candidates fail in
three of four cases in clinical trials, together with increased costs and increased demands of …

Le fluor 18 en radiopharmacie

V De Beco, D Le Bars, JM Scherrmann - Annales pharmaceutiques …, 2008 - Elsevier
Positron emission tomography (PET) is a recent and expanding functional nuclear imaging
technique. Its extensive development is related to the radiophysical properties fluorine 18 …

PET radionuclide production

SM Qaim, JC Clark, C Crouzel, M Guillaume… - … for positron emission …, 1993 - Springer
Several short-lived positron-emitters are routinely used in PET studies while a few others are
of potential interest. A brief review of the decay data and production methods for several of …